Results 41 to 50 of about 827,357 (223)

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

Is the demonstration of bioequivalence for clavulanic acid required in amoxicillin–clavulanic acid orally administered immediate-release products?

open access: yes, 2018
Objectives Bioequivalence (BE) criteria for amoxicillin–clavulanic acid (Co-amoxiclav) oral formulations are based on 90% confidence interval for both amoxicillin and clavulanic acid.
Areeg Anwer Ali   +2 more
core   +1 more source

HLA‐A*11:01 Identifies Patients at Risk for Persistent Viraemia and Advanced Fibrosis in HDV Infection

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The HLA‐A*11:01 allele is associated with persistent viraemia and advanced liver fibrosis in HDV infection. HLA‐A*11:01 carriers exhibit a reduced T‐cell repertoire, suggesting a narrower T‐cell response to the infection. ABSTRACT Background Hepatitis delta virus (HDV) infection causes the most severe form of viral hepatitis, with highly heterogeneous ...
Maria Francesca Cortese   +11 more
wiley   +1 more source

Hypersensitivity to clavulanic acid in children

open access: yesAllergologia et Immunopathologia, 2008
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/
M, Tortajada Girbés   +5 more
openaire   +2 more sources

Ocular and cutaneous infection due to Curvularia pseudobrachyspora in an immunosuppressed dog: Case report and in vitro antimycotic susceptibilities

open access: yesAustralian Veterinary Journal, EarlyView.
A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa   +4 more
wiley   +1 more source

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women [PDF]

open access: yes, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Roos, N.M., de, Katan, M.B., Bots, M.L.
core  

Effect of Membrane Perforations With and Without Collagen Membrane Coverage in Vertical Ridge Augmentation: An Experimental Pilot In Vivo Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives Given the proposed bioactive role of collagen membranes, we aimed to evaluate whether the perforation size of titanium‐reinforced dPTFE membranes, with or without an additional collagen membrane, influences outcomes of vertical alveolar ridge augmentation (VARA).
Istvan A. Urban   +7 more
wiley   +1 more source

An evaluation of the pharmacokinetic safety and efficacy of ticarcillin/clavulanic acid in the treatment of bacterial infections in hospitalized elderly subjects [PDF]

open access: yes, 1986
dissertationThe geriatric population has an increased incidence of infections, which results in appreciable morbidity and mortality. Alterations in host defense mechanisms with aging contribute to the increased risk of infection.
Roost, Charlotte
core  

A Two-component Regulatory System Involved in Clavulanic Acid Production

open access: yes, 2008
A pair of genes encoding the bacterial two-component regulatory system, orf22 and orf23, was found next to the clavulanic acid gene cluster of Streptomyces clavuligerus NRRL3585. Orf23 was deleted for the construction of S.
Byoung Chul Park   +8 more
core   +1 more source

Clinical Efficacy of CBCT and 3D‐Printed Replicas in Molar Autotransplantation: A Controlled Clinical Trial

open access: yesDental Traumatology, Volume 41, Issue 2, Page 161-170, April 2025.
ABSTRACT Background/Aim To evaluate the efficacy of the combined cone‐beam (CBCT)/3D‐replicas protocol on the clinical and radiographic outcomes of autotransplanted molars. Material and Methods Controlled clinical trial registered ISRCTN13563091 from August 2019 to September 2022.
Miks Lejnieks   +4 more
wiley   +1 more source

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