Results 41 to 50 of about 5,976,595 (218)

Gut Bacterial Microbiota and its Resistome Rapidly Recover to Basal State Levels after Short-term Amoxicillin-Clavulanic Acid Treatment in Healthy Adults

open access: yesScientific Reports, 2018
Clinical effects of antimicrobials and probiotics in combination have been reported, however, little is known about their impact on gut microbiota and its resistome.
Chad W. MacPherson   +6 more
semanticscholar   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Impact of oral amoxicillin and amoxicillin/clavulanic acid treatment on bacterial diversity and β-lactam resistance in the canine faecal microbiota.

open access: yesJournal of Antimicrobial Chemotherapy, 2019
BACKGROUND Aminopenicillins with or without a β-lactamase inhibitor are widely used in both human and veterinary medicine. However, little is known about their differential impact on the gut microbiota and development of antimicrobial resistance ...
C. Espinosa-Gongora   +14 more
semanticscholar   +1 more source

Treatment of discospondylitis in dogs: A systematic review

open access: yesVeterinary Record, EarlyView.
Abstract Background Both medical and surgical techniques have been reported to manage canine discospondylitis, although data on clinical effectiveness and long‐term prognosis remain limited. Methods A systematic review of studies on treatment approaches, follow‐up data and investigation methods was conducted.
Vasileios Ioannis Vallios   +4 more
wiley   +1 more source

Identification of an antigenic determinant of clavulanic acid responsible for IgE‐mediated reactions

open access: yesAllergy. European Journal of Allergy and Clinical Immunology, 2019
Selective reactions to clavulanic acid (CLV) account for around 30% of immediate reactions after administration of amoxicillin‐CLV. Currently, no immunoassay is available for detecting specific IgE to CLV, and its specific recognition in patients with ...
N. Barbero   +11 more
semanticscholar   +1 more source

Patterns of Surgical Prophylaxis Prescribing for Dentoalveolar Procedures in Australian Hospitals: 2016–2022

open access: yesAustralian Dental Journal, EarlyView.
ABSTRACT Background Antimicrobials are an adjunctive therapy in clinical dentistry. In dentoalveolar surgery, antimicrobials are not routinely required for surgical prophylaxis. This retrospective analysis of the Australian Surgical National Antimicrobial Prescribing Survey (Surgical NAPS) dataset aimed to evaluate the guideline compliance and ...
Jane Chen   +6 more
wiley   +1 more source

Comparative Genomics and Metabolomics Analyses of Clavulanic Acid-Producing Streptomyces Species Provides Insight Into Specialized Metabolism

open access: yesFrontiers in Microbiology, 2019
Clavulanic acid is a bacterial specialized metabolite, which inhibits certain serine β-lactamases, enzymes that inactivate β-lactam antibiotics to confer resistance.
Nader AbuSara   +9 more
semanticscholar   +1 more source

Development of Betalactam‐Predictor: A Clinical Decision Tool for Delabeling Low‐Risk Betalactam Allergy Patients. Initial Validation in Penicillin Allergy

open access: yesAllergy, EarlyView.
BL‐Predictor has emerged as a new tool for delabeling penicillin allergy. External validation has shown a specificity of 93% for detecting low‐risk patients. This score could potentially reduce diagnostic costs and the negative consequences associated with incorrect antibiotic allergy labels.
Marina Labella   +14 more
wiley   +1 more source

Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy

open access: yesAllergy, EarlyView.
DeAns with defined nanoscale structure reveal that conjugate size and determinant density govern IgE‐mediated effector‐cell activation in AX allergy. All DeAn generations bind to sIgE in inhibition immunoassay, but only larger DeAns trigger FcεRI‐dependent responses in mouse MC, huRBL‐2H3, and LUVA cells.
Amene Tesfaye Ayane   +12 more
wiley   +1 more source

Hypersensitivity to clavulanic acid in children

open access: yesAllergologia et Immunopathologia, 2008
We present 10 cases (6 males and 4 females) of children aged 4 to 12 years, who were diagnosed with allergy to clavulanic acid (CL) and treated in the Paediatric Allergy Section of the University Hospital Dr. Peset in Valencia from 2000 to 2005. The children reported symptoms of urticaria and angio-oedema after receiving orally-administered amoxicillin/
M, Tortajada Girbés   +5 more
openaire   +2 more sources

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