Results 31 to 40 of about 9,985 (247)

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Development of a β-lactamase-based aggregation-induced emission lateral flow strip for the detection of clavulanic acid in Milk

Food Chemistry: X
Lack of biorecognition elements significantly hinders the development of rapid detection methods for clavulanic acid (CA). To address this, we expressed Class A β-lactamases PC1 in vitro and demonstrated its high affinity for CA. Then we investigated the
Xiaonan Wang, Tong He, Leina Dou, Licai Ma, Xuezhi Yu, Zhanhui Wang, Kai Wen   +6 more
doaj   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

British Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst, Pieter‐Jan Spiessens, Dorian Vanneste, Nada Dia, Matthias Gijsen, Isabel Spriet, Karel Allegaert, Erwin Dreesen, Anne Smits   +8 more
wiley   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

Isolation and Identification of Pseudomonas aeruginosa from Soil Contaminated with Petroleum Products

Journal of Pure and Applied Microbiology
The amount of petroleum hydrocarbons affects biodegradation. Different classifications can be used to petroleum components Asphaltenes, ethers, fatty acids, porphyrins and resins saturated fatty acids.
Zahraa M. Al-Taee, Y.M. Liqaa, Rafal Ahmed Lilo, Aamal Muhsen Kadhum, Farah Mumtaz, Hadi Sajid Abdulabbas, Essam Murad Yousif, Autaf Talal Shaker, Mustafa Abdulrahman A. Al-kinani   +8 more
doaj   +1 more source

Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR analysis and docking studies [PDF]

, 2013
Aim and Methods: Although the antimicrobial activity of extracts from several mushroom species have been reported, studies with the individual compounds present in that extracts are scarce.
Abreu, Rui M.V., Alves, Maria José, Ferreira, Isabel C.F.R., Froufe, Hugo J.C., Martins, Anabela, Pintado, Manuela   +5 more
core   +1 more source

Subperiosteal peri‐implant augmented layer to correct bone dehiscence at immediate implant placement

Clinical Advances in Periodontics, EarlyView.
Abstract Background The purpose of the present case report is to describe the potential of the subperiosteal peri‐implant augmented layer (SPAL) technique in peri‐implant bone dehiscence (PIBD) correction at immediate implant placement (IIP). Methods This case report describes the application of the SPAL technique in two patients undergoing IIP at ...
Tommaso Grenzi, Chiara Franzini, Mattia Severi, Leonardo Trombelli   +3 more
wiley   +1 more source

Characteristics of Escherichia coli Isolated from bovine mastitis exposed to subminimum inhibitory concentrations of cefalotin or ceftazidime [PDF]

, 2018
Escherichia coli is a major udder pathogen causing clinical mastitis in dairy cattle and its heat stable endotoxin in powdered infant formula milk is a potential risk factor in neonatal infections.
Ali, Tariq, Barkema, Herman, De Vliegher, Sarne, Ding, Laidi, Gao, Jian, Han, Bo, Liu, Gang, Naqvi, S Ali, Piepers, Sofie, Xu, Siyu   +9 more
core   +2 more sources

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source