Preliminary evaluation of probiotic properties of Lactobacillus strains isolated from Sardinian dairy products [PDF]
, 2014 Twenty-three Lactobacillus strains of dairy origin were evaluated for some functional properties relevant to their use as probiotics. A preliminary subtractive screening based on the abilities to inhibit the growth of microbial pathogens and hydrolyze ...
Conti S +7 more
core +1 more source
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]
, 2012 Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
A Freitag +59 more
core +6 more sources
Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]
, 2010 More than half of all currently used antibiotics belong to the beta-lactam group, but their clinical effectiveness is severely limited by antibiotic resistance of microorganisms that are the causative agents of infectious diseases. Several mechanisms for
A. A. Medeiros +127 more
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PLoS ONE, 2019 In Streptomyces clavuligerus, the gene cluster involved in the biosynthesis of the clinically used β-lactamase inhibitor clavulanic acid contains a gene (orf12 or cpe) encoding a protein with a C-terminal class A β-lactamase-like domain.
Santosh K Srivastava +6 more
doaj +1 more source
Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]
, 2017 Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina +15 more
core +2 more sources
Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]
, 2018 The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher +13 more
core +2 more sources
Multidrug-resistant Escherichia coli, Klebsiella pneumoniae and Staphylococcus spp. in houseflies and blowflies from farms and their environmental settings [PDF]
, 2019 Background: Antimicrobial resistance is rising globally at an alarming rate. While multiple active surveillance programs have been established to monitor the antimicrobial resistance, studies on the environmental link to antimicrobial spread are lacking.
Adekanmbi, Folesade +10 more
core +1 more source
National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae, France, 2014 [PDF]
, 2016 From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national ...
Dortet, L +3 more
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Optimization of clavulanic acid production by Streptomyces daufpe 3060 by response surface methodology [PDF]
, 2011 Clavulanic acid is a β-lactam antibiotic which has a potent β-lactamase inhibiting activity. In order to optimize its production by the new isolate Streptomyces DAUFPE 3060, the influence of two independent variables, temperature and soybean ...
ARAÚJO, Janete M. +6 more
core +2 more sources
Structural and Functional Aspects of Class A Carbapenemases. [PDF]
, 2016 The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core +3 more sources