Results 11 to 20 of about 827,357 (223)

Influence of free amino acids on clavulanic acid production by Streptomyces clavuligerus in synthetic medium

, 2006
The effect of nitrogen source on clavulanic acid production was investigated in shake flasks. Media containing asparagine plus one of several different amino acids or a combination of two amino acids was tested. The best result, ca.
Trovatti, Eliane, Badino, Alberto Colli, Hokka, Carlos Osamu, Gonsales da Costa Araujo, Maria Lucia   +3 more
core   +4 more sources

Treatment of moderate grade dog bite wounds using amoxicillin–clavulanic acid with and without enrofloxacin: a randomised non‐inferiority trial

, 2021
Background: Dog-to-dog bite wounds are a common veterinary emergency presentation: despite this, there is insufficient information to guide veterinarians on appropriate empirical antimicrobial management.
M Haworth, Haworth, Mark, C Croton, Croton, Catriona, JS Gibson, AJ Stewart, Kalnins, Nicole, Gibson, Justine, Purcell, Sarah, SL Purcell, Stewart, Allison, NJ Kalnins   +11 more
core   +1 more source

Production of clavulanic acid and cehphamycin C by Stretpmyces clavuligerus in palm oil medium [PDF]

, 1996
Palm and palm-kernel oils and their olein and stearin fractions were suitable as the main carbon sources for growth and production of clavulanic acid by Streptomyces clavuligerus. However, oleic and lauric acids were not utilized for growth.
Lee, Ping Chin, C C Ho
core   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus

Synthetic and Systems Biotechnology, 2017
The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such strains ...
Eser Ünsaldı, Aslıhan Kurt-Kızıldoğan, Birgit Voigt, Dörte Becher, Gülay Özcengiz   +4 more
doaj   +1 more source

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Puhl, G., Neuhaus, P., Schön, M. R., Hammer, C., Matthes, M., Heil, W., Lemmens, H.-P., Padval, D.   +7 more
core   +1 more source

Dynamic kinetic resolution-mediated synthesis of C-3 hydroxylated arginine derivatives

Royal Society Open Science
Hydroxylated amino acids and their derivatives, including those found in proteins, are important in biology and medicinal chemistry. Incubation of N-acetyl-l-arginine with clavaminic acid synthase, a key oxygenase in clavulanic acid biosynthesis, affords
Ye Zheng, Zhenyu Chen, Guy J. Clarkson, Stephen A. Marshall, Jianliang Xiao, Christopher J. Schofield, Martin Wills, Andrew V. Stachulski   +7 more
doaj   +1 more source

Overproduction of clavulanic acid by extractive fermentation [PDF]

, 2015
BackgroundClavulanic acid is an important beta-lactamase inhibitor produced as a secondary metabolite by the actinomycete Streptomyces clavuligerus. Clavulanic acid is chemically unstable; therefore, it is degraded during bacterial cultivation.
Badino, Alberto Colli, Colli Badino,Alberto, Lopes Costa,Cecília Ladeira, Cecília Ladeira Lopes Costa, Costa, Cecília Ladeira Lopes, Alberto Colli Badino, Costa, Cec\uedlia Ladeira Lopes   +6 more
core   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]

, 2012
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
Kierzek, A.M., Eriko Takano (50986), Breitling, Rainer, Albert Gevorgyan, Gevorgyan, A., Breitling, R., Breitling, Rainer,, Andrzej M Kierzek, Zakrzewski, Piotr, Breitling Rainer, Gevorgyan Albert, Piotr Zakrzewski (111739), Piotr Zakrzewski, Rainer Breitling (4371), Eriko Takano, Medema, M.H., Takano, Eriko,, Zakrzewski Piotr, Gevorgyan, Albert, Takano Eriko, Kierzek, Andrzej M., Zakrzewski, P., Takano, E., Rainer Breitling, Medema Marnix H., Gevorgyan, Albert,, Marnix H. Medema (111741), Medema, Marnix H.,, Medema, Marnix H., Albert Gevorgyan (111745), Andrzej M. Kierzek (111748), Kierzek Andrzej M., Takano, Eriko, Zakrzewski, Piotr,, Marnix H Medema, Takano, Eriko; id_orcid, Kierzek, Andrzej M.,, Breitling, R, Medema, MH, Kierzek, AM, Zakrzewski, P, Gevorgyan, A, Takano, E   +42 more
core   +4 more sources