Results 81 to 90 of about 61,784 (267)

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Prevalência de aditivos alimentares em produtos industrializados e a tendência clean label

open access: yes, 2023
Introduction: The ingestion of food additives in processed foods can impact human health. Considering this, the clean label trend arises with healthier and more natural ingredients.
Costa, Leilliane de Moura   +2 more
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

ECLIPSE: Expunging Clean-Label Indiscriminate Poisons via Sparse Diffusion Purification

open access: yes
ECLIPSE: Expunging Clean-Label Indiscriminate Poisons via Sparse Diffusion ...
Shengshan Hu (13429977)   +7 more
core   +2 more sources

Analysis of the development of modifying loss functions in label-noise environments [PDF]

open access: yesITM Web of Conferences
In recent years, the rapid advance of artificial intelligence has intensified interest in deep learning. However, during the training process of deep learning, the paper found that it is often susceptible to label noise.
Jin Liang
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Dairy ingredients as clean label additives

open access: yes, 2019
Clean label bi lahko označili kot gibanje oz. prizadevanja potrošnikov, ki stremijo k bolj zdravemu načinu življenja, kar vključuje tudi uživanje zdravih živil. Njihova glavna zahteva je vrnitev k pravim, avtentičnim živilom, ki vsebujejo naravne, znane,
Matić, Kristina
core   +1 more source

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