Results 51 to 60 of about 276,111 (308)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

J~#-Uc cleanness and strongly J~#-Uc cleanness of rings

Nantong Daxue xuebao. Ziran kexue ban
A ring R is GU_cJ if U(R)=Uc(R)+J~#(R);R is (strongly) J~#-U_c-clean ring if for any a∈R,there exists g∈Uc(R),p2=p∈R,d∈J~#(R),such that ag=p+d (and ap=pa).GU_cJ rings and J~#-U_c-clean rings are proper generalizations of GUJ rings and GJ-clean rings ...
JIN Danya; HUANG Tao; CUI Jian
doaj   +1 more source

Tripotents: a class of strongly clean elements in rings

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2018
Periodic elements in a ring generate special classes of strongly clean elements. In particular, elements b such that b = b3+, which are called tripotents and include idempotents, negative of idempotents and order 2 units, are strongly clean.
Călugăreanu Grigore
doaj   +1 more source

On graded nil clean rings [PDF]

Communications in Algebra, 2018
In this paper we introduce and study the notion of a graded (strongly) nil clean ring which is group graded. We also deal with extensions of graded (strongly) nil clean rings to graded matrix rings and to graded group rings. The question of when nil cleanness of the component, which corresponds to the neutral element of a group, implies graded nil ...
Ilic-Georgijevic, Emil, Sahinkaya, Serap
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Some properties of skew Hurwitz series

Le Matematiche, 2014
In this paper we show that, if R is a ring and σ an endomorphism of R, then the skew Hurwitz series ring T = (HR, σ ) is an n-clean ring if and only if R is an n-clean ring.
A. M. Hassanein, Mohamed A. Farahat
doaj  

⁎-Clean rings; some clean and almost clean Baer ⁎-rings and von Neumann algebras

Journal of Algebra, 2010
A ring is clean (resp. almost clean) if each of its elements is the sum of a unit (resp. regular element) and an idempotent. In this paper we define the analogous notion for *-rings: a *-ring is *-clean (resp. almost *-clean) if its every element is the sum of a unit (resp. regular element) and a projection.
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Rings in which elements are the sum of a nilpotent and a root of a fixed polynomial that commute

Open Mathematics, 2017
An element in a ring R with identity is said to be strongly nil clean if it is the sum of an idempotent and a nilpotent that commute, R is said to be strongly nil clean if every element of R is strongly nil clean. Let C(R) be the center of a ring R and g(
Handam Ali H., Khashan Hani A.
doaj   +1 more source