Results 61 to 70 of about 2,286,730 (346)
Surface micromachined mechanisms and micromotors [PDF]
, 1991 Electric micromotors are sub-millimeter sized actuators capable of unrestrained motion in at least one degree of freedom. Polysilicon surface micromachining using heavily phosphorus-doped LPCVD polysilicon for the structural material, LPCVD silicon ...
Mehregany, Mehran, Tai, Yu-Chong
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Design and Evaluation of the LOPES Exoskeleton Robot for Interactive Gait Rehabilitation [PDF]
, 2007 This paper introduces a newly developed gait rehabilitation device. The device, called LOPES, combines a freely translatable and 2-D-actuated pelvis segment with a leg exoskeleton containing three actuated rotational joints: two at the hip and one at the
Asseldonk, Edwin H.F. van +5 more
core +2 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The Effects of Joint Clearance on the Dynamics of the 3-RPR Planar Parallel Manipulator [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2018 In reality, clearances in the joints are inevitable due to the defects arising from manufacturing process, design tolerances, and wearing after a certain working period.
Seyyed Mojtaba Varedi-Koulaei +1 more
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Three-dimensional study for the relative positioning of mechanical elements in mechanisms constituted by parrallel joints with clearances [PDF]
, 2014 The great evolution of the data-processing tools during the last years allowed for the development of the computer aided design in the field of mechanical structures.
DAL SANTO, Philippe +2 more
core +2 more sources
Design of a tribological ball joint tester [PDF]
, 2015 The automotive industry uses ball joints in the suspension systems of cars. These ball joints are subject to various forces and relative displacements which inevitably invoke wear.
De Baets, Patrick +3 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Shoulder and hip joint for hard space suits [PDF]
, 1986 Shoulder and hip joints for hard space suits are disclosed which are comprised of three serially connected truncated spherical sections, the ends of which converge. Ball bearings between the sections permit relative rotation.
Vykukal, H. C.
core +1 more source