Results 61 to 70 of about 1,284,621 (297)
eLifeThe expression of eukaryotic genes relies on the precise 3'-terminal cleavage and polyadenylation of newly synthesized pre-mRNA transcripts. Defects in these processes have been associated with various diseases, including cancer.
Yaroslav Kainov +2 more
doaj +1 more source
Metal-Assisted Hydrolysis Reactions Involving Lipids: A Review
Frontiers in Chemistry, 2019 This report covers major advances in the use of metal ions and complexes to hydrolyze ester and phosphate ester lipid bonds. These metal-based Lewis acids have been investigated as catalysts to isolate fatty acids from biological sources, as probes to ...
Dominique E. Williams, Kathryn B. Grant
doaj +1 more source
Weak Topological Insulators and Composite Weyl Semimetals: $\beta$-Bi$_{4}$X$_{4}$ (X=Br, I)
, 2015 While strong topological insulators (STI) have been experimentally realized soon after their theoretical predictions, a weak topological insulator (WTI) has yet to be unambiguously confirmed.
Liu, Cheng-Cheng +3 more
core +1 more source
Double strand DNA cleavage with a binuclear iron complex [PDF]
, 2007 Covalently linking two single strand DNA cleaving agents resulted in a new biomimetic binuclear iron complex capable of effecting oxidative double strand DNA cleavage.
Berg, Tieme A. van den, +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Error correction during DNA replication
, 2012 DNA polymerase (DNAP) is a dual-purpose enzyme that plays two opposite roles in two different situations during DNA replication. It plays its normal role as a {\it polymerase} catalyzing the elongation of a new DNA molecule by adding a monomer.
Chowdhury, Debashish, Sharma, Ajeet K.
core +1 more source
Transcript profiling for early stages during embryo development in Scots pine [PDF]
, 2016 Background: Characterization of the expression and function of genes regulating embryo development in conifers is interesting from an evolutionary point of view.
Abrahamsson, Malin +5 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Unique Appearance of Lamellar Cleavage Patterns on Fracture Surfaces of Ti-Based Amorphous Matrix Composite [PDF]
In order to improve mechanical properties of Ti-based amorphous matrix composites basically composed of ductile beta-Ti dendrites and brittle amorphous matrix by overcoming their inherent brittle nature, their fracture mechanisms should be verified in ...
Jeon, C +5 more
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source