Results 51 to 60 of about 895,341 (164)

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP [PDF]

open access: yes, 2000
The 3' ends of most eukaryotic pre-mRNAs are generated by 3' endonucleolytic cleavage and subsequent polyadenylation. 3'-end formation can be influenced positively or negatively by various factors.
Gunderson, S. I.   +4 more
core  

Cleavage-defective MALT1_R781L as well as catalytically-inactive MALT1_C464A affects the growth of HBL-1 cells.

open access: yes, 2018
HBL-1 cells were lentivirally transduced with doxycycline-inducible expression vectors for MALT1, MALT1_1–781, MALT1_R781L, MALT1_C464A, MALT1B, MALT1B_1–770, or MALT1B_R770L. (A) Expression levels of endogenous and various transduced forms of MALT1 at 4
Yu-Hsuan Yang (5464682)   +5 more
core   +1 more source

ON THE POSSIBLE FORMATION MECHANISM OF THE OPEN FRACTURING IN SEDIMENTARY BASINS

open access: yesГеодинамика и тектонофизика
The paper shows that the formation of orthogonal systems of open macrofractures (cleavages) of sedimentary basins can occur at the stage of diagenesis during the first hundreds of years for a small range of shelf depths (up to 100 m) during sedimentation.
Yu. L. Rebetsky
doaj   +1 more source

The Role of Prion Protein in Reelin/Dab1 Signaling: Implications for Neurodegeneration

open access: yesViruses
The cellular prion protein (PrPC) is studied in prion diseases, where its misfolded isoform (PrPSc) leads to neurodegeneration. PrPC has also been implicated in several physiological functions.
Irene Giulia Rolle   +4 more
doaj   +1 more source

Application of N-Bromosuccinimide in Carbohydrate Chemistry

open access: yesSynOpen, 2023
Smritilekha Bera   +2 more
doaj   +1 more source

Metabolism of Zearalenone and Its Major Modified Forms in Pigs

open access: yesToxins, 2017
The Fusarium mycotoxin zearalenone (ZEN) can be conjugated with polar molecules, like sugars or sulfates, by plants and fungi. To date, the fate of these modified forms of ZEN has not yet been elucidated in animals.
Sabina B. Binder   +6 more
doaj   +1 more source

Towards Understanding Trans-Cleavage of Natural and Synthetic Nucleic Acids by Cas12a for Sensitive CRISPR Biosensing [PDF]

open access: yes
CRISPR/Cas systems have been widely utilized for the development of biosensing platforms for precision molecular diagnostics. Their remarkable biosensing performance critically depends on the efficiency of sequence-independent trans-cleavage in type V ...
Wei , Deng   +5 more
core   +2 more sources

Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites

open access: yesViruses, 2019
Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases.
Si Chen   +8 more
doaj   +1 more source

Kinetics of Pre-mRNA 3’ End Cleavage [PDF]

open access: yes
3’ end cleavage and polyadenylation are required steps in pre-mRNA maturation. The rate at which 3’ end cleavage occurs can determine the temporal availability of mRNA for subsequent function throughout the cell and is likely tightly regulated.
Torres Ulloa, Leslie
core   +1 more source

Dicer-like Enzymes with Sequence Cleavage Preferences [PDF]

open access: yes, 2018
Dicer proteins are known to produce small RNAs (sRNAs) from long double-stranded RNA (dsRNA) templates. These sRNAs are bound by Argonaute proteins, which select the guide strand, often with a 5′ end sequence bias. However, Dicer proteins have never been
Iris Hug   +5 more
core   +2 more sources

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