Results 31 to 40 of about 1,284,621 (297)
Coupling of actin hydrolysis and polymerization: Reduced description with two nucleotide states
, 2010 The polymerization of actin filaments is coupled to the hydrolysis of adenosine triphosphate (ATP), which involves both the cleavage of ATP and the release of inorganic phosphate.
Abramowitz M. +6 more
core +1 more source
Research and Practice in Thrombosis and HaemostasisBackground: Type 2A von Willebrand disease (VWD) is characterized by impaired platelet adhesion due to the selective loss of high-molecular-weight von Willebrand factor (VWF) multimers. Objectives: To investigate A2 domain variants underlying type 2A VWD
Omid Seidizadeh +7 more
doaj +1 more source
Role for polo-like kinase 4 in mediation of cytokinesis. [PDF]
, 2019 The mitotic protein polo-like kinase 4 (PLK4) plays a critical role in centrosome duplication for cell division. By using immunofluorescence, we confirm that PLK4 is localized to centrosomes.
Brugge, Joan S +10 more
core +2 more sources
Normal cohesive strength of cement mortar in the masonry [PDF]
Инженерно-строительный журнал, 2012 Normal cohesion of stone and mortar and strength to stretch of mortar in masonry joints depend on many factors that are hardly taken into account in evaluating the normal cohesive strength of stone and mortar.
V.N. Derkach
doaj
The C-terminal portion of the cleaved HT motif is necessary and sufficient to mediate export of proteins from the malaria parasite into its host cell [PDF]
, 2012 The malaria parasite exports proteins across its plasma membrane and a surrounding parasitophorous vacuole membrane, into its host erythrocyte. Most exported proteins contain a Host Targeting motif (HT motif) that targets them for export. In the parasite
Cryar, Adam +4 more
core +1 more source
Viruses, 2020 The Gammacoronavirus infectious bronchitis virus (IBV) causes a highly contagious and economically important respiratory disease in poultry. In the laboratory, most IBV strains are restricted to replication in ex vivo organ cultures or in ovo and do not ...
Phoebe Stevenson-Leggett +2 more
doaj +1 more source
Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending [PDF]
, 2016 Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicobacter
Adams +71 more
core +4 more sources
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
, 2018 CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
SNAC-tag for sequence-specific chemical protein cleavage. [PDF]
, 2019 Site-specific protein cleavage is essential for many protein-production protocols and typically requires proteases. We report the development of a chemical protein-cleavage method that is achieved through the use of a sequence-specific nickel-assisted ...
Dang, Bobo +5 more
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