Results 11 to 20 of about 1,284,621 (297)

The RSV F p27 peptide: current knowledge, important questions

open access: yesFrontiers in Microbiology, 2023
Respiratory syncytial virus (RSV) remains a leading cause of hospitalizations and death for young children and adults over 65. The worldwide impact of RSV has prioritized the search for an RSV vaccine, with most targeting the critical fusion (F) protein.
Wanderson Rezende   +5 more
doaj   +1 more source

Mass spectrometry of the phosphatidylcholines: fragmentation processes for dioleoyl and stearoyl-oleoyl glycerylphosphorylcholine

open access: yesJournal of Lipid Research, 1971
Mass spectra for the various phosphatidylcholines, together with accurate mass measurements on the more abundant fragment ions, have been described in a previous paper (Ref. 5).
R.A. KLEIN
doaj   +1 more source

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

open access: yesmBio, 2022
The continuous emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) urges better understanding of the functional motifs in the spike (S) protein and their tolerance to mutations.
Annelies Stevaert   +7 more
doaj   +1 more source

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP [PDF]

open access: yes, 2000
The 3' ends of most eukaryotic pre-mRNAs are generated by 3' endonucleolytic cleavage and subsequent polyadenylation. 3'-end formation can be influenced positively or negatively by various factors.
Vagner, S.   +4 more
core   +1 more source

Pseudotrypsin: A Little-Known Trypsin Proteoform

open access: yesMolecules, 2018
Trypsin is the protease of choice for protein sample digestion in proteomics. The most typical active forms are the single-chain β-trypsin and the two-chain α-trypsin, which is produced by a limited autolysis of β-trypsin.
Zdeněk Perutka, Marek Šebela
doaj   +1 more source

Intercalation Technology for Preparing a Mica–Organic Hybrid Solid Lubricant and Spectroscopic Evaluation of Its Lubrication Mechanism

open access: yesTribology Online, 2019
The lubrication behavior of mica–alkyl ammonium cation hybrid solid lubricants fabricated via an intercalation reaction was evaluated by reciprocating sliding tests, and the lubrication mechanism was investigated from the viewpoint of interlayer adhesion
Kenichiro Oshita   +2 more
doaj   +1 more source

Ectodomain shedding of the amyloid precursor protein: Cellular control mechanisms and novel modifiers [PDF]

open access: yes, 2006
Proteolytic cleavage in the ectodomain of the amyloid precursor protein (APP) is a key regulatory step in the generation of the Alzheimer's disease amyloid-beta (A beta) pepticle and occurs through two different protease activities termed alpha- and beta-
Lichtenthaler, Stefan F.
core   +1 more source

Components required for in vitro cleavage and polyadenylation of eukaryotic mRNA [PDF]

open access: yes, 1988
We have studied in vitro cleavage/polyadenylation of precursor RNA containing herpes simplex virus type 2 poly A site sequences and have analysed four RNA/protein complexes which form during in vitro reactions.
Clements, J.B.   +3 more
core   +1 more source

Domains and Functions of Spike Protein in SARS-Cov-2 in the Context of Vaccine Design

open access: yesViruses, 2021
The spike protein in SARS-CoV-2 (SARS-2-S) interacts with the human ACE2 receptor to gain entry into a cell to initiate infection. Both Pfizer/BioNTech’s BNT162b2 and Moderna’s mRNA-1273 vaccine candidates are based on stabilized mRNA encoding prefusion ...
Xuhua Xia
doaj   +1 more source

Selective inhibition of carotenoid cleavage dioxygenases : phenotypic effects on shoot branching [PDF]

open access: yes, 2009
Members of the carotenoid cleavage dioxygenase family catalyse the oxidative cleavage of carotenoids at various chain positions, leading to the formation of a wide range of apocarotenoid signalling molecules.
Auldridge   +52 more
core   +1 more source

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