The hyaluronan-binding serine protease from human plasma cleaves HMW and LMW kininogen and releases bradykinin [PDF]
The influence of the hyaluronanbinding protease (PHBSP), a plasma enzyme with FVII- and pro-urokinase-activating potency, on components of the contact phase (kallikrein/kinin) system was investigated.
Beer, N. +4 more
core +1 more source
Cloning and characterisation of a maize carotenoid cleavage dioxygenase (ZmCCD1) and its involvement in the biosynthesis of apocarotenoids with various roles in mutualistic and parasitic interactions [PDF]
Colonisation of maize roots by arbuscular mycorrhizal (AM) fungi leads to the accumulation of apocarotenoids (cyclohexenone and mycorradicin derivatives).
Beekwilder, M.J. +10 more
core +2 more sources
PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment
Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the LDL receptor (LDLR) at the cell surface and reroutes the internalized LDLR to intracellular degradation.
Kristian Tveten +3 more
doaj +1 more source
Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Duda, Erno +4 more
core +1 more source
Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Andress +15 more
core +1 more source
(1) Background: Meningiomas are usually benign encapsulated intracranial tumors with well-defined borders that offer a high chance of cure with complete removal.
Nazmin Ahmed +10 more
doaj +1 more source
The efficient preparation of novel bioactive peptide drugs requires the availability of reliable and accessible chemical methodologies together with suitable analytical techniques for the full characterisation of the synthesised compounds.
Roser Segovia +4 more
doaj +1 more source
Seneca Valley virus 3C protease cleaves HDAC4 to antagonize type I interferon signaling
Seneca Valley virus (SVV) is a newly identified pathogen that poses a notable threat to the global pig industry. SVV has evolved multiple strategies to evade host antiviral innate immune responses.
Zijian Li +8 more
doaj +1 more source
Alegerile parlamentare din 11 decembrie 2016: clivaje politice vechi, noi şi viitoare [PDF]
The article is based on the assumption that the outstanding PSD electoral results in December 2016 are the final result of a political framework transformation that has its origin in the financial crisis 0f 2009.
Radu CARP
doaj
Zebrafish Embryos Display Characteristic Bioelectric Signals during Early Development
Bioelectricity is defined as endogenous electrical signaling mediated by the dynamic distribution of charged molecules. Recently, increasing evidence has revealed that cellular bioelectric signaling is critical for regulating embryonic development ...
Martin R. Silic +4 more
doaj +1 more source

