Mitochondria localize to the cleavage furrow in mammalian cytokinesis. [PDF]
PLoS ONE, 2013 Mitochondria are dynamic organelles with multiple cellular functions, including ATP production, calcium buffering, and lipid biosynthesis. Several studies have shown that mitochondrial positioning is regulated by the cytoskeleton during cell division in ...
Elizabeth J Lawrence, Craig A Mandato
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Centrosomes: CNN's broadcast reaches the cleavage furrow. [PDF]
Curr Biol, 2009 Centrosomin (CNN), a core Drosophila centrosome protein, interacts with the newly identified protein Centrocortin to promote cleavage furrow formation in the early embryo. Significantly, this activity is distinct from CNN's well-established role in centrosome-based microtubule organization.
Sullivan W.
europepmc +6 more sources
Vesicles and actin are targeted to the cleavage furrow via furrow microtubules and the central spindle [PDF]
The Journal of Cell Biology, 2008 During cytokinesis, cleavage furrow invagination requires an actomyosin-based contractile ring and addition of new membrane. Little is known about how this actin and membrane traffic to the cleavage furrow.
Albertson, Roger +3 more
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Actin hitches a ride to the cleavage furrow [PDF]
J Cell Biol, 2008 ![Graphic][1] Time-lapse images show packages of actin (red, arrows) at the cleavage furrow of a dividing cell. When it comes to efficient packing and shipping, FedEx doesn't have anything on a dividing cell.
Mitch Leslie
europepmc +5 more sources
Delivery of ceramide phosphoethanolamine lipids to the cleavage furrow through the endocytic pathway is essential for male meiotic cytokinesis. [PDF]
PLoS Biology, 2022 Cell division, wherein 1 cell divides into 2 daughter cells, is fundamental to all living organisms. Cytokinesis, the final step in cell division, begins with the formation of an actomyosin contractile ring, positioned midway between the segregated ...
Govind Kunduri +11 more
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A lipid regulator working at the cleavage furrow. [PDF]
Cell Cycle, 2016 Cytokinesis occurs during the last phase of cell division and distributes the cytoplasm of one parent cell into 2 daughter cells.
Eto K, Denda H, Funato K.
europepmc +5 more sources
Cleavage-furrow formation without F-actin in Chlamydomonas. [PDF]
Proc Natl Acad Sci U S A, 2020 AbstractIt is widely believed that cleavage-furrow formation during cell division is driven by the contraction of a ring containing F-actin and type-II myosin. However, even in cells that have such rings, they are not always essential for furrow formation.
Onishi M, Umen JG, Cross FR, Pringle JR.
europepmc +7 more sources
Specific detection of fission yeast primary septum reveals septum and cleavage furrow ingression during early anaphase independent of mitosis completion. [PDF]
PLoS Genetics, 2018 It is widely accepted in eukaryotes that the cleavage furrow only initiates after mitosis completion. In fission yeast, cytokinesis requires the synthesis of a septum tightly coupled to cleavage furrow ingression.
Juan Carlos G Cortés +9 more
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Advances in Cytokinesis Research. On the Mechanism of Cleavage Furrow Ingression in Dictyostelium.
Cell Structure and Function, 2001 The ability of Dictyostelium cells to divide without myosin II in a cell cycle-coupled manner has opened two questions about the mechanism of cleavage furrow ingression. First, are there other possible functions for myosin II in this process except for generating contraction of the furrow by a sliding filament mechanism?
I.T. Weber
openalex +6 more sources
Unilateral Cleavage Furrows in Multinucleate Cells [PDF]
Cells, 2020 Multinucleate cells can be produced in Dictyostelium by electric pulse-induced fusion. In these cells, unilateral cleavage furrows are formed at spaces between areas that are controlled by aster microtubules.
Julia Bindl +5 more
doaj +7 more sources