Results 121 to 130 of about 14,699 (328)

Bioengineered Models of Nerve Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
Bioengineered nerve regeneration platforms ranging from patterned cell cultures and hydrogels to fibrous scaffolds and microfluidic systems are reviewed, highlighting the complex cellular and biochemical environments essential for nerve repair. Challenges associated with these platforms, such as balancing complexity with throughput and the need for ...
Madalynn Jade Thompson   +1 more
wiley   +1 more source

Possible origins of macroscopic left-right asymmetry in organisms

open access: yes, 2012
I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules.
A. Tamada   +100 more
core   +1 more source

Chromosomal Deficiencies and the Embryonic Development of Drosophila Melanogaster [PDF]

open access: yes, 1937
Chromosome aberrations have marked effects upon the development of an organism. Many such aberrations are lethal. In Drosophila this is particularly true of chromosomal deficiencies, as first described by Bridges [2]. A more detailed study of the effects
Poulson, D. F.
core   +1 more source

Polarization Management on Anisotropic Thin‐Film Lithium Niobate Platform

open access: yesAdvanced Photonics Research, EarlyView.
This review focuses on x‐cut thin‐film lithium niobate (TFLN), exploring strategies to mitigate anisotropy and mode hybridization. It covers polarization beam splitters, rotators, splitter‐rotators, polarizers, and polarization‐insensitive components. Key applications include polarization‐division multiplexing, polarization‐insensitive modulation, and ...
Kaixuan Chen   +9 more
wiley   +1 more source

Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]

open access: yes, 2015
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Baum, B   +3 more
core   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

open access: yesAdvanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian   +10 more
wiley   +1 more source

The septin cytoskeleton facilitates membrane retraction during motility and blebbing. [PDF]

open access: yes, 2012
Increasing evidence supports a critical role for the septin cytoskeleton at the plasma membrane during physiological processes including motility, formation of dendritic spines or cilia, and phagocytosis.
Chen, Yi-Chun M   +3 more
core  

The Molecular Basis of Amino Acids Sensing

open access: yesAdvanced Science, EarlyView.
Amino acids are essential as protein building blocks and signaling molecules, enabling metabolic regulation. Cells sense amino acid levels to control protein synthesis, maintain homeostasis, and adapt to nutritional changes. This review explores recent advances in amino acid sensing mechanisms across organisms, highlighting their roles in cellular ...
Cong Jiang   +3 more
wiley   +1 more source

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

open access: yesAdvanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park   +9 more
wiley   +1 more source

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