Results 171 to 180 of about 14,699 (328)

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

open access: yesThe Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen   +3 more
wiley   +1 more source

Tight junction formation in early Xenopus laevis embryos: identification and ultrastructural characterization of junctional crests and junctional vesicles [PDF]

open access: yes, 2018
How tight junctions (TJ) form during early amphibian embryogenesis is still an open question. We used time-lapse video microscopy, scanning electron microscopy (SEM), TEM and freeze-fracture to gain new insight into TJ biogenesis in early clevages of ...
Cardellini, Pietro   +2 more
core  

Covalent Peptide‐Graphene Conjugates for Enhanced Cell Spreading, Osteogenic Differentiation, and Angiogenesis in Bone Defects

open access: yesChemBioChem, EarlyView.
The three peptides RGD, DGEA, and KKGHK are covalently attached to the 2D nanomaterial graphene oxide (GO) to create new biomaterials for the treatment of severe bone injuries. These GO modifications improve cell spreading, stem cell differentiation into bone cell types, and formation of blood vessel‐like structures.
Michelle E. Wolf   +4 more
wiley   +1 more source

Development and Recent Advances in SLIPT‐PM: A Chemogenetic Platform for Manipulating Signaling at the Plasma Membrane

open access: yesChemBioChem, Accepted Article.
Upon cell stimulation, mammalian cells activate various signaling proteins and lipids by recruiting their upstream regulators to the inner leaflet of the plasma membrane (PM), which in turn determines their cellular response. Therefore, artificially inducing protein translocation to the PM is an effective strategy for dissecting cell signaling networks
Shuya Ohira   +3 more
wiley   +1 more source

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes

open access: yesChemBioChem, EarlyView.
Group II Introns (G2Is) are large self‐splicing ribozymes with promising biotechnological applications. This study utilized RNA inverse folding to design three novel G2Is. The designed intron Arq.I2, an unexpectedly proficient ribozyme, self‐splices not only in vitro, but also in Escherichia coli cells.
Deni Szokoli   +3 more
wiley   +1 more source

Light‐Activated Molecules Targeting G‐Quadruplex Nucleic Acids

open access: yesChemistry – A European Journal, EarlyView.
We shine a spotlight on the molecular recognition mechanisms and phototherapeutic potential of light‑activated compounds targeting G‑quadruplex nucleic acids, critically evaluating recent breakthroughs and charting the key challenges that must be overcome to drive this promising field forward.
Marta Dudek   +2 more
wiley   +1 more source

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