Results 11 to 20 of about 14,699 (328)
Alpha-actinin localization in the cleavage furrow during cytokinesis. [PDF]
The Journal of cell biology, 1978 We used antibodies against alpha-actinin and myosin labeled directly with contrasting fluorochromes to localize these contractile proteins simultaneously in dividing chick embryo cells. During mitosis anti-alpha-actinin stains diffusely the entire cytoplasm including the mitotic spindle, while in the same cells intense antimyosin staining delineates ...
Kazuko Fujiwara +2 more
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IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning [PDF]
Nature Communications, 2017 Cytokinesis relies on central spindle organization and provides a spatial landmark for lumen formation. Here, the authors show that intraflagellar transport proteins are required for the localization of the cytokinetic regulator Aurora B and subsequent ...
Nicolas Taulet +8 more
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Cleavage furrow positioning [PDF]
The Journal of Cell Biology, 2004 To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells.
Glotzer, Michael
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Cytokinesis in vertebrate cells initiates by contraction of an equatorial actomyosin network composed of randomly oriented filaments [PDF]
eLife, 2017 The actomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its filament organization and the mechanism of contractility is not well understood.
Felix Spira +8 more
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Positioning the cleavage furrow: All you need is Rho. [PDF]
J Cell Biol, 2016 RhoA controls cleavage furrow formation during cell division, but whether RhoA suffices to orchestrate spatiotemporal dynamics of furrow formation is unknown. In this issue, Wagner and Glotzer (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603025) show that RhoA activity can induce furrow formation in all cell cortex positions and cell cycle ...
Liu Z, Weiner OD.
europepmc +5 more sources
Cleavage furrow establishment by the moving mitotic apparatus [PDF]
Development, Growth & Differentiation, 1997 The midpoint of the mitotic apparatus is fixed in the future division plane long before the division mechanism develops, and this static relationship has been considered essential in speculations concerning division mechanism establishment. The purpose of the present investigation was to determine whether prevention of the static relationship affects ...
R. Rappaport
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PtdIns(4,5)P2 Functions at the Cleavage Furrow during Cytokinesis [PDF]
Current Biology, 2005 SummaryPhosphoinositides play important roles in regulating the cytoskeleton and vesicle trafficking, potentially important processes at the cleavage furrow.
Cantley, Lewis C. +7 more
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Two-step positioning of a cleavage furrow by cortexillin and myosin II [PDF]
Current Biology, 2000 Myosin II, a conventional myosin, is dispensable for mitotic division in Dictyostelium if the cells are attached to a substrate, but is required when the cells are growing in suspension. Only a small fraction of myosin II-null cells fail to divide when attached to a substrate.
I.T. Weber +5 more
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Rappaport rules: Cleavage furrow induction in animal cells
Proceedings of the National Academy of Sciences, 1997 Cytokinesis in animal cells is achieved by a circumferential ring of differentiated cortex, enriched in actin and myosin, that contracts to divide the cytoplasm (reviewed in ref. 1). The placement of the contractile ring is specified by the mitotic apparatus such that contraction bisects the mitotic spindle, ensuring that division occurs between the ...
Karen Oegema, Timothy J. Mitchison
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A spindle-independent cleavage furrow positioning pathway. [PDF]
Nature, 2010 The mitotic spindle determines the cleavage furrow site during metazoan cell division, but whether other mechanisms exist remains unknown. Here we identify a spindle-independent mechanism for cleavage furrow positioning in Drosophila neuroblasts.
Cabernard C, Prehoda KE, Doe CQ.
europepmc +6 more sources