Results 291 to 300 of about 316,097 (341)

Skin lesion triage in organ transplant recipients using line‐field confocal optical coherence tomography: a retrospective classification study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background/objectives: Organ transplant recipients (OTRs) face an elevated risk of keratinocyte carcinomas (KC), leading to a lower threshold for biopsy. Line‐field confocal optical coherence tomography (LC‐OCT) is a non‐invasive imaging technique capable of visualizing malignant skin changes, yet its role in the management of OTRs remains ...
Kevin Jacobsen   +4 more
wiley   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

open access: yesThe FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim   +8 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source
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Regulation of the cytokinesis cleavage furrow by PKCε.

Biochemical Society Transactions, 2014
Cytokinesis is the final act of the cell cycle where the replicated DNA and cellular contents are finally split into two daughter cells. This process is very tightly controlled as DNA segregation errors and cytokinesis failure is commonly associated with aneuploidy and aggressive tumours.
N. Brownlow   +4 more
semanticscholar   +4 more sources

Visualization of cleavage furrow proteins in fixed dividing spermatocytes.

Methods in Cell Biology, 2017
Cytokinesis separates the cytoplasmic organelles and the duplicated genome into two daughter cells at the end of cell division. In animal cell cytokinesis, assembly and constriction of the contractile apparatus must be finely coordinated with plasma membrane remodeling and vesicle trafficking at the cleavage furrow.
A. Frappaolo   +4 more
semanticscholar   +5 more sources

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