Results 41 to 50 of about 14,699 (328)

Polar relaxation by dynein-mediated removal of cortical myosin II [PDF]

open access: yes, 2020
Nearly 6 decades ago, Lewis Wolpert proposed the relaxation of the polar cell cortex by the radial arrays of astral microtubules as a mechanism for cleavage furrow induction (White and Borisy, 1983; Wolpert, 1960).
Balasubramanian, Mohan K.   +4 more
core   +1 more source

Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster [PDF]

open access: yesOpen Biology, 2017
Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is
Stefano Sechi   +8 more
doaj   +1 more source

Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos. [PDF]

open access: yesPLoS ONE, 2017
Myosin-1 (Myo1) represents a mechanical link between the membrane and actin-cytoskeleton in animal cells. We have studied the effect of Myo1 inhibitor PClP in 1-8 cell Zebrafish embryos.
Prabuddha Gupta   +4 more
doaj   +1 more source

Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow [PDF]

open access: yesThe EMBO Journal, 1999
The fact that substrate-anchored Dictyostelium cells undergo cytokinesis in the absence of myosin II underscores the importance of other proteins in enabling the cleavage furrow to constrict. Cortexillins, a pair of actin-bundling proteins, are required for normal cleavage.
Weber, Igor   +7 more
openaire   +5 more sources

Cytokinesis D is Mediated by Cortical Flow of Dividing Cells Instead of Chemotaxis

open access: yesCells, 2019
Cytokinesis D is known as the midwife mechanism in which neighboring cells facilitate cell division by crossing the cleavage furrow of dividing cells.
Yuki Tanaka   +4 more
doaj   +1 more source

Spatiotemporal recruitment of RhoGTPase protein GRAF inhibits actomyosin ring constriction in Drosophila cellularization

open access: yeseLife, 2021
Actomyosin contractility is regulated by Rho-GTP in cell migration, cytokinesis and morphogenesis in embryo development. Whereas Rho activation by Rho-GTP exchange factor (GEF), RhoGEF2, is well known in actomyosin contractility during cytokinesis at the
Swati Sharma, Richa Rikhy
doaj   +1 more source

A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells. [PDF]

open access: yes, 1981
After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin.
CANDE, W. Zacheus   +2 more
core   +2 more sources

A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin.

open access: yesPLoS ONE, 2013
Recently, we demonstrated that integrin adhesion to the extracellular matrix at the cleavage furrow is essential for cytokinesis of adherent cells.
Saara Hämälistö   +8 more
doaj   +1 more source

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments [PDF]

open access: yesOncogene, 1999
The small GTPase Rho and one of its targets, Rho-associated kinase (Rho-kinase), are implicated in a wide spectrum of cellular functions, including cytoskeletal rearrangements, transcriptional activation and smooth muscle contraction. Since Rho also plays an essential role in cytokinesis, Rho-kinase may possibly mediate some biological aspects of ...
Kaori Matsuzawa   +9 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy