Minor Kinases with Major Roles in Cytokinesis Regulation
Cytokinesis, the conclusive act of cell division, allows cytoplasmic organelles and chromosomes to be faithfully partitioned between two daughter cells.
Stefano Sechi+2 more
doaj +1 more source
Astral Signals Spatially Bias Cortical Myosin Recruitment to Break Symmetry and Promote Cytokinesis [PDF]
SummaryBackgroundAfter anaphase, the segregated chromosomes are sequestered by cytokinesis into two separate daughter cells by a cleavage furrow formed by the actomyosin-based contractile ring.
Glotzer, Michael+2 more
core +1 more source
Background Cortical myosin-II filaments in Dictyostelium discoideum display enrichment in the posterior of the cell during cell migration and in the cleavage furrow during cytokinesis. Filament assembly in turn is regulated by phosphorylation in the tail
Spudich James A+4 more
doaj +1 more source
Effects of wounds in the cell membrane on cell division
Cells are consistently subjected to wounding by physical or chemical damages from the external environment. We previously showed that a local wound of the cell membrane modulates the polarity of cell migration and the wounded cells escape from the wound ...
Md. Istiaq Obaidi Tanvir+1 more
doaj +1 more source
Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis [PDF]
Cytokinesis is a highly ordered cellular process driven by interactions between central spindle microtubules and the actomyosin contractile ring linked to the dynamic remodelling of the plasma membrane.
Tetsuya Takeda+6 more
doaj +1 more source
Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion
Summary: During cytokinesis, a contractile ring consisting of unbranched filamentous actin (F-actin) and myosin II constricts at the cell equator. Unbranched F-actin is generated by formin, and without formin no cleavage furrow forms.
Mikhail Lebedev+8 more
doaj
Live cell interferometry quantifies dynamics of biomass partitioning during cytokinesis.
The equal partitioning of cell mass between daughters is the usual and expected outcome of cytokinesis for self-renewing cells. However, most studies of partitioning during cell division have focused on daughter cell shape symmetry or segregation of ...
Thomas A Zangle+2 more
doaj +1 more source
Peripheral astral microtubules ensure asymmetric furrow positioning in neural stem cells [PDF]
Neuroblast division is characterized by asymmetric positioning of the cleavage furrow, resulting in a large difference in size between the future daughter cells.
Arnal I+7 more
core +2 more sources
Dynamics of Myosin II Filaments during Wound Repair in Dividing Cells
Wound repair of cell membranes is essential for cell survival. Myosin II contributes to wound pore closure by interacting with actin filaments in larger cells; however, its role in smaller cells is unclear.
Md. Istiaq Obaidi Tanvir+3 more
doaj +1 more source
Syntaxin 16 is a master recruitment factor for cytokinesis [PDF]
Recently it was shown that both recycling endosome and endosomal sorting complex required for transport (ESCRT) components are required for cytokinesis, in which they are believed to act in a sequential manner to bring about secondary ingression and ...
Alexandra Kaupisch+48 more
core +2 more sources