Results 41 to 50 of about 1,796 (161)

Cleidocranial dysplasia presenting with retained deciduous teeth and impacted permanent and supernumerary teeth

Journal of Indian Academy of Oral Medicine and Radiology, 2014
Cleidocranial dysplasia is a disease that occurs secondary to a dominant autosomal inheritance. There is no predilection for any genre or ethnic group. As there is a delay in the eruption and/or absence of permanent teeth, the patients usually report to ...
Mahalakshmi Ikkanur Puttaranganaik, Tejavathi Nagaraj, Suchetha Devendrappa Nadig, Pooja Sinha   +3 more
doaj   +1 more source

GSK-3beta controls osteogenesis through regulating Runx2 activity.

PLoS ONE, 2007
Despite accumulated knowledge of various signalings regulating bone formation, the molecular network has not been clarified sufficiently to lead to clinical application.
Fumitaka Kugimiya, Hiroshi Kawaguchi, Shinsuke Ohba, Naohiro Kawamura, Makoto Hirata, Hirotaka Chikuda, Yoshiaki Azuma, James R Woodgett, Kozo Nakamura, Ung-il Chung   +9 more
doaj   +1 more source

Prosthetic rehabilitation of a patient with cleidocranial dysplasia using dental implants—a clinical report

International Journal of Implant Dentistry, 2021
Adult patients with oral manifestations of untreated syndromic malformations usually exhibit a high degree of suffering. In this clinical report, we describe the implant-supported prosthetic treatment of a patient with cleidocranial dysplasia, a rare ...
Sigmar Schnutenhaus, Werner Götz, Ralph G. Luthardt   +2 more
doaj   +1 more source

Continuous supernumerary teeth development in cleidocranial dysplasia post-surgical extraction – A novel case report

Advances in Oral and Maxillofacial Surgery, 2023
The diagnosis of Cleidocranial dysplasia is approached via clinical features, genetic testing, and imaging. CCD includes delayed or non-closure of cranial sutures the presence of bulging anterior fontanelle and multiple supernumerary teeth. We report two
Faisal Joueidi, Ahmad Joueidi, Yanal Nusair, Fuad Al Mutairi, Samar Al Hayek   +4 more
doaj   +1 more source

Expanding Spectrum of FIG4‐Related Neurological Disorders of Lysosomal Homeostasis: Case Report and Overview of the Potential Genotype–Phenotype Correlations

Clinical Genetics, EarlyView.
FIG4 is essential for lysosomal homeostasis. FIG4‐related disorders present as a continuous spectrum from the juvenile lethality in Yunis‐Varon syndrome to an increased risk of amyotrophic lateral sclerosis (ALS) in adult life. FIG4‐related disorders comprise a novel group of disorders of lysosomal homeostasis and can be classified into severe ...
Pankaj Prasun, Matthew Rasberry
wiley   +1 more source

A Dual Control Study on the Treatment of Adolescent Skeletal Class III Malocclusion With Customised Titanium Plate Bone‐Anchored Maxillary Protraction

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective To explore the effect of personalised titanium plate Bone‐anchored maxillary protraction (BAMP) on the maxillofacial structure of adolescents with skeletal Class III malocclusion. Methods A total of 20 patients with skeletal Class III malocclusion were selected as the treatment group 1 (TG1) with treatment using individualised BAMP ...
Yang Liu, Shukui Xu, Linna Wang, Yuze Zhang, Junli Chen, Xueming Shi, Xinyu Xie, Wensheng Ma   +7 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, Volume 293, Issue 12, Page 3502-3527, June 2026.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Agrin Ablation in Osteoblasts Compromises Long Bone Structure and Osteoblastic Differentiation of Mesenchymal Stem Cells

Journal of Cellular Biochemistry, Volume 127, Issue 5, May 2026.
ABSTRACT Agrin is an important factor in maintaining skeletal architecture. However, the role of osteoblast‐expressed agrin in bone tissue remains unexplored. Thus, we hypothesized that agrin‐deficient osteoblasts negatively affect bone tissue homeostasis by disrupting osteoblastic differentiation of mesenchymal stem cells (MSCs).
Gabriela Camarneiro Siqueira, Maria Paula Oliveira Gomes, Letícia Faustino Adolpho, Aline Ying Ying Wang, Fabiola Singaretti Olveira, Adriana Luisa Gonçalves Almeida, Roger Rodrigo Fernandes, Ana Paula Macedo, Ana Paula Ramos, Adalberto Luiz Rosa, Marcio Mateus Beloti   +10 more
wiley   +1 more source

Cleidocranial dysplasia: A report of two cases

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Cleidocranial dysplasia (CCD) is an autosomal dominant disorder that presents with skeletal dysplasia. It commonly presents with significant dental problems such as retention of multiple deciduous teeth, impaction or delay in eruption of permanent teeth,
D N Mehta, R V Vachhani, M B Patel
doaj   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, Volume 46, Issue 5-6, Page 849-861, May 2026.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source