Results 51 to 60 of about 72,220 (148)
Frontiers in Genetics, 2021 Cleidocranial dysplasia (CCD; OMIM 119600) is a rare autosomal dominant skeletal dysplasia, which is mainly characterized by persistently open or delayed closure of fontanelle, patent skull sutures, abnormal clavicles, pectus excavatum, short stature ...
Ru Xue +3 more
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Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background and Aim As dental anomalies can significantly affect esthetic and function, early detection and diagnosis are crucial for treatment and minimizing potential negative effects. Artificial intelligence (AI) has emerged as a promising tool for the segmentation and detection of dental anomalies in number, morphology, size, position, and ...
Mobina Sadat Zarabadi +4 more
wiley +1 more source
Runx2 Regulated Airway Homeostasis Is Disrupted in Asthma
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.Runt‐related transcription factor‐2 (RUNX2) expression and regulation of airway remodeling factors were examined in asthmatic and nonasthmatic airway smooth muscle (ASM) cells. Regulation by transforming growth factor‐β of active RUNX2 isoform translocation to the nucleus was absent in asthmatic ASM, while RUNX2 overexpression suppressed markers of ...
Junfei Wang +13 more
wiley +1 more source
Multidisciplinary management of cleidocranial dysplasia [PDF]
, 2015 Background: Cleidocranial dysplasia (CCD), also known as cleidocranial dysostosis or osteodental dysplasia, is an autosomal dominant disorder caused by a microdeletion defect in chromosome 6p21.
Chalala, Chimène +3 more
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CLEIDOCRANIAL DYSPLASIA, NEUROFIBROMATOSIS TYPE-I WITH FRONTAL LOBE GLIOMA
Pakistan Armed Forces Medical Journal, 2005 Introduction Cleidocranial Dysplasia is a benign hereditary condition, inherited as an autosomal dominant. The disease has considerable variation of expression. Thirty percent of the cases are due to spontaneous mutation [1]. The gene responsible for
Muhammad Nazir, Asim Rafiq
doaj +2 more sources
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.MECP2 insufficiency leads to upregulation of miR‐126‐3p, which in turn enhances the endogenous Wnt antagonist DKK1. DKK1 inhibits the canonical Wnt signaling pathway, thereby impairing RUNX2‐dependent osteoblast differentiation. ABSTRACT Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by loss‐of‐function mutations in the gene encoding ...
Shuangshan Dong +12 more
wiley +1 more source
American Journal of Human Biology, Volume 38, Issue 2, February 2026.ABSTRACT Objective To characterize the metacarpophalangeal pattern profile (MCPP) of healthy children and adolescents from São Paulo, Brazil, and to establish percentile curves by chronological age (CA), bone age (BA), and sex using the LMS method. Additionally, to compare these findings with previous population‐based data and to apply the derived ...
Marcelo Damaso Maruichi +4 more
wiley +1 more source
A Rare Case Report of Four Bilateral Maxillary Lateral Incisors in a Non‐Syndromic Patient
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT Bilateral supernumerary maxillary lateral incisors in non‐syndromic adults are extremely rare and pose diagnostic and treatment challenges. This case report describes a 34‐year‐old male with esthetic concerns and malocclusion, successfully managed through strategic extraction, transverse expansion, and fixed orthodontic therapy, achieving ...
Seyed‐Mohsen Hosseini‐Adib +1 more
wiley +1 more source
Case Reports in Dentistry, Volume 2026, Issue 1, 2026.Introduction Missing teeth in growing patients require treatment approaches that preserve alveolar bone and support continued development. Autotransplantation offers a biological alternative to implants, yet severely compromised recipient sites and immature donor teeth present clinical challenges.
Miks Lejnieks +6 more
wiley +1 more source
Orthodontic and surgical management of cleidocranial dysplasia
, 2013 Cleidocranial dysplasia (CCD), an autosomal dominant disorder with a prevalence of 1 in 1,000,000 individuals, is mainly caused by mutations in Runx2, a gene required for osteoblastic differentiation.
Vargervik, Karin, Oberoi, Snehlata
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