Pycnodysostosis : a report of 3 clinical cases [PDF]
, 2008 Pycnodysostosis is a rare clinical entity, first described in 1962 by Maroteaux and Lamy. It is a genetic disorder, usually diagnosed at an early age.
Alves Pereira, Daniela +2 more
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Case Reports in Dentistry, Volume 2026, Issue 1, 2026.Background Osteopetrosis is a rare genetic disorder characterized by increased bone density due to defective osteoclast function. Its clinical presentation varies according to subtype, and oral manifestations are frequent, potentially serving as early indicators of the disease.
Maria Amalia Cruz-Morera +3 more
wiley +1 more source
Mesiodens preventing eruption of a permanent central incisor [PDF]
, 2005 A maxillary midline supernumerary tooth is the most common type of supernumerary tooth. We present a case of a mesiodens, preventing eruption of a permanent central incisor.
Azzopardi, Alexander +2 more
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Retardo en la erupción dental en adolescentes con hipotiroidismo [PDF]
, 2012 OBJECTIVE: To report the case of an adolescent with undiagnosed hypothyroidism who sought dental clinic care due to delayed tooth eruption. Multiprofessionalwork enabled the diagnosis.
Braga, Josefina Aparecida Pellegrini +3 more
core +4 more sources
High Expression of IGSF10 Confers an Inhibitory Effect on the Progression of Lung Adenocarcinoma
Journal of Cellular and Molecular Medicine, Volume 29, Issue 24, December 2025.ABSTRACT Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer‐related deaths worldwide. Unlike conventional treatments, the targeted therapies or emerging immunotherapies have shown significant advantages in the management of advanced lung cancer.
Lianyu Cheng +5 more
wiley +1 more source
The PI3K/AKT/mTOR Pathway and Oral Diseases: A Bibliometric Analysis From 2008 to 2025
Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.ABSTRACT Objectives The phosphoinositide 3 kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway is a key therapeutic target for oral diseases. This study uses bibliometric analysis to identify research trends, knowledge gaps, and the development of PI3K/AKT/mTOR‐targeted therapies.
Yena Gan +7 more
wiley +1 more source
Interactions between extracellular signal‐regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity [PDF]
, 2012 RUNX2, a key transcription factor for osteoblast differentiation, is regulated by ERK1/2 and p38 MAP kinase‐mediated phosphorylation. However, the specific contribution of each kinase to RUNX2‐dependent transcription is not known. Here we investigate ERK
Franceschi, Renny T. +5 more
core +1 more source
Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells [PDF]
, 2012 It has previously been demonstrated that cell shape can influence commitment of human bone marrow-derived mesenchymal stem cells (hBMCs) to adipogenic, osteogenic, chondrogenic, and other lineages.
Chen, Christopher S. +2 more
core +2 more sources
Clinical and genetic study on a cleidocranial dysplasia family [PDF]
Kouqiang yixueObjective To confirm the mutation in a family with cleidocranial dysplasia (CCD) and explore its possible effects on protein structure and function.
ZHANG Xinyu, MAO Ji, CHENG Tingting, MA Lan, CHENG Liming, PAN Yongchu
doaj +1 more source
Mechanisms and molecular regulation of mammalian tooth replacement [PDF]
, 2008 In most non-mammalian vertebrates, such as fish and reptiles, teeth are replaced continuously. However, tooth replacement in most mammals, including human, takes place only once and further renewal is apparently inhibited.
Järvinen, Elina
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