Results 151 to 160 of about 10,001 (185)

Cytotoxic clerodane diterpenoids from Croton crassifolius

Bioorganic & Medicinal Chemistry Letters, 2017
Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and treatment options for HCC are limited. In addition, the discovery of new natural compounds with anti-hepatocarcinoma activity is attracting increasing attention. For this reason, phytochemical investigation of Croton crassifolius led to the isolation of 17 diterpenoids ...
Jin-Long, Tian, Guo-Dong, Yao, Yu-Xi, Wang, Pin-Yi, Gao, Di, Wang, Ling-Zhi, Li, Bin, Lin, Xiao-Xiao, Huang, Shao-Jiang, Song   +8 more
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Clerodane and aromatic seco-clerodane diterpenoids from salvia rhyacophua.

Tetrahedron, 1991
Abstract The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were isolated from Salvia rhyacophila together with five new clerodane diterpenoids 3-6 and 12. The structures of diterpenes 3-6 were established on spectral evidence and chemical transformations.
María del Carmen Fernández, Baldomero Esquivel, Jorge Cárdenas, Ana Adela Sánchez, Ruben Alfredo Toscano, Lydia Rodríguez-Hahn   +5 more
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Neo-clerodane diterpenoids fromTeucrium gracile

Phytochemistry, 1991
Abstract Four new neo -clerodane diterpenoids have been isolated from the aerial parts of Teucrium gracile . The structures of these compounds, 3β,19-diacetoxy-4α,18;15,16-diepoxy-6β-hydroxy- neo -cleroda-13(16),14-dien-20,12 S olide (teugracilin A), 19-acetoxy-4α,18;15,16-diepoxy-3β,6β-dihydroxy- neo -cleroda-13(16),14-dien-20,12 S -olide (3- O ...
Maurizio Bruno, Gema Domi´nguez, Ana Lourenço, Franco Piozzi, Benjami´n Rodri´guez, Giuseppe Savona, Mari´a C. De la Torre, Nelly A. Arnold   +7 more
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Cytotoxic activity of neo-clerodane diterpenoids

Bioorganic & Medicinal Chemistry Letters, 1997
Abstract Several neo-clerodane diterpenoids isolated from extracts of roots and aerial parts of Linaria saxatilis var. glutinosa, as well as some semisynthetic derivatives, exhibited in vitro growth inhibition against different neoplastic cell cultures. A number of substances showed IC50 values under 1μM.
Marina Gordaliza, JoséM. Miguel del Corral, María Luz de la Puente, María Dolores Garcia-Grávalos, Arturo San Feliciano   +4 more
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Clerodane diterpenoids from Salvia melissodora

Phytochemistry, 1988
Abstract From two populations of Salvia melissodora Lag., four neo-clerodane diterpenoids were isolated. The structures of these compounds were established by spectroscopic and chemical means. The triterpenoids, oleanolic acid and ursolic acid, together with sitosterol, were also found in this species.
Baldomero Esquivel, Alfonso Vallejo, Rubén Gaviño, Jorge Cárdenas, Ana-Adela Sánchez, T.P. Ramamoorthy, Lydia Rodriguez-Hahn   +6 more
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ent-Clerodane diterpenoids from the stems of Croton krabas

Fitoterapia, 2021
The first phytochemical investigation from the stems of Croton krabas resulted in the isolation of three new ent-clerodane diterpenoids, crotonkrabases A-C (1-3), along with two known compounds, 12-oxohardwickiic acid (4) and crotonpyrone B (5). Their structures were elucidated using extensive spectroscopic methods. The structure of 3 was unambiguously
Oue-Artorn, Rajachan, Waranya, Lakornwong, Siripit, Pitchuanchom, Natcha P, Suchaichit, Jaursup, Boonmak, Sujittra, Youngme, Kwanjai, Kanokmedhakul, Somdej, Kanokmedhakul   +7 more
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Clerodane diterpenoids from Aster alpinus

Phytochemistry, 1985
Abstract The aerial parts of Aster alpinus afforded, in addition to dammadienyl acetate and dammadienone, two clerodane derivatives related to salviarin and bacchotricuneatin A. The structures were elucidated by spectroscopic methods, especially high-field NMR. The chemotaxonomic situation is discussed briefly.
Ferdinand Bohlmann, Jasmin Jakupovic, Mohyeddin Hashemi-Nejad, Siegfried Huneck   +3 more
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Clerodane Diterpenoids from Kinostemon alborubrum

Helvetica Chimica Acta, 2002
Three new clerodane diterpenoids, kinalborin A (1), B (2), and C(3), together with six known diterpenoids, teuperin A (4), montanin E (5), teulamifin B (6), teuflin (7), montanin D (8), and teupernin B (9), have been isolated from the whole plant of Kinostemon alborubrum (HEMSL.) C. Y. Wu et S. CHOW, a Chinese endemic herb.
Deng Ye, Peng Shu-Lin, Zhang Qiang, Liao Xun, Ding Li-Sheng   +4 more
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Clerodane diterpenoids from Salvia urolepis

Phytochemistry, 1995
Abstract From the aerial parts of Salvia urolepis , three new neoclerodane diterpenoids were isolated. Their structures were determined by spectroscopic means. The known languidulane diterpenoid 2 α -hydroxy-7- epi -8 β , 17-dihydro-languiduline was also obtained.
Ana Adela Sanchez, Baldomero Esquivel, T.P. Ramamoorthy, Lydia Rodriguez-Hahn   +3 more
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Clerodane Diterpenoids From Croton Hemiargyreus

Natural Product Letters, 1998
Abstract Two new clerodane furano-diterpenes, 9-methoxycarbonyl-15, 16-epoxy-cleroda-3, 13(16), 14-trien-2-one (cromiargyne-1a) and 7-acetoxy-9-methoxywrbonyl-15,16-expoxy-cleroda-3,13(16), 14-trien-2-one (7-acetoxy-cromiargyne – 1b). were isolated from the bark of Croton hemiargyreus (Euphorbiaceae).
Ana Claudia F. Amaral, Roderick A. Barnes   +1 more
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