A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily ...
Luiza Baptista de Oliveira Freitas +5 more
doaj +1 more source
Netml-ns3-click: Modeling of Routers in Netml/ns3 by means of the Click Modular Router
In this paper the design, development and use of a facility to run ns3 simulations, including Click routers, of networks constructed by the Netml system for analysis and design of networks in the cloud is described.
Ronald Addie, Joshua Natarajan
doaj +1 more source
Unbiased Learning to Rank with Unbiased Propensity Estimation
Learning to rank with biased click data is a well-known challenge. A variety of methods has been explored to debias click data for learning to rank such as click models, result interleaving and, more recently, the unbiased learning-to-rank framework ...
Ai, Qingyao +4 more
core +1 more source
An Assessment of the Scholarship of Teaching and Learning in Public Administration from 2009-2013 [PDF]
The acceptance of the Scholarship of Teaching and Learning (SoTL) as a legitimate form of scholarly investigation and the shape that it takes in post-secondary education are inherently discipline-specific.
Rebekkah Stuteville, Eric Click
doaj +2 more sources
Exoskeleton for Biofunctionality Protection of Enzymes and Proteins for Intracellular Delivery
Driven by the challenges to protect and restore biofunctionality of enzymes and proteins due to fluctuation of temperature, pH, and solvents, desired tolerances against the intracellular microenvironment can be gained via sheltering enzyme and proteins ...
Saikat Dutta
doaj +1 more source
Recent Advances in Transition Metal-Catalyzed Ring-Opening Reaction of Aziridine
The smallest strained, saturated N-heterocycles, such as aziridine, can be a valuable building block in synthetic organic chemistry. Ring-opening reactions with various nucleophiles could be the most important strategy to synthesize various value-added ...
Partha Sarathi Bera +3 more
doaj +1 more source
Relationship between Development and Divorce in Iran Mansour Dayhoul , Sirous Ahmadi , Asghar Mirfardi [PDF]
The purpose of this study was to investigate the relationship between socioeconomic development and divorce in Iran during the years 1392-1396. The present research is quantitative-longitudinal and has been done by time series method.
Mansuor Dayhuol, s a, Asghar Mirfardi
doaj +1 more source
Experiential negative symptoms (ENS) of schizophrenia, such as asociality, anhedonia, and avolition, are associated with poor outcomes, yet no FDA-approved pharmacotherapies currently exist specifically to target these symptoms.
Haig Goenjian +15 more
doaj +1 more source
Recent Advances in Click Chemistry Applied to Dendrimer Synthesis
Dendrimers are monodisperse polymers grown in a fractal manner from a central point. They are poised to become the cornerstone of nanoscale devices in several fields, ranging from biomedicine to light-harvesting. Technical difficulties in obtaining these
Mathieu Arseneault +2 more
doaj +1 more source
Enzymatic Cross-Linking of Dynamic Thiol-Norbornene Click Hydrogels [PDF]
Enzyme-mediated in situ forming hydrogels are attractive for many biomedical applications because gelation afforded by enzymatic reactions can be readily controlled not only by tuning macromer compositions, but also by adjusting enzyme kinetics.
Hudson, Britney N. +3 more
core +2 more sources

