Results 131 to 140 of about 2,703,843 (291)

Click Chemistry

Drug Delivery System, 2023
Suguru Yoshida, Tomoki Nishimura
openaire   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Prospects of click chemistry reactions in nuclear medicine: the TCO-Tz reaction based on the IEDDA mechanism

Nuclear Medicine Review
Click chemistry reactions, characterized by their high efficiency, strong selectivity, unique in vivo pre-targeting capabilities, and bioorthogonality, have shown great promise in nuclear medicine in recent years.
Yufeng Jing, Jiameng Liu, Chaoming Mao, Yufei Mao   +3 more
doaj   +1 more source

Reactions under the Click Chemistry Philosophy Employed in Supramolecular and Mechanostereochemical Systems

, 2011
Supramolecular chemistry and mechanostereochemistry have been major beneficiaries of the concepts and reactions pioneered under the "click chemistry" philosophy. The success of the copper(I) 1,3-dipolar cycloaddition between azides and alkynes, resulting
Albert C. Fahrenbach, J. Fraser Stoddart, Stoddart, J. Fraser, Fahrenbach, Albert C.   +3 more
core   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Sulfonamide-modified tetrazines as bioorthogonal tools for click-to-release reactions.

, 2022
reservedBioorthogonal chemistry can be defined as a toolbox of reactions that proceed rapidly and selectively in biological environments without reacting with other potential functional groups naturally present among the myriad of biomolecules ...
YAGHI, FATIMA
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The application of click chemistry for targeting quadruplex nucleic acids

, 2019
The Cu(i)-catalyzed azide and alkyne 1,3-dipolar cycloaddition (CuAAC), commonly known as the “click reaction”, has emerged as a powerful and versatile synthetic tool that finds a broad spectrum of applications in chemistry, biology and materials science.
Dash, Jyotirmayee, Panda, Deepanjan, Saha, Puja   +2 more
core   +1 more source

New High‐Tc Charge‐Transfer Multiferroicity in the Quasi‐2D Antiferromagnet CrSbS3

Advanced Science, EarlyView.
ABSTRACT Low‐dimensional magnets, particularly 2D systems, offer a rich platform for realizing unconventional multiferroic mechanisms, especially when multiple polarization channels coexist. In the quasi‐2D antiferromagnet CrSbS3, which crystallizes in the centrosymmetric orthorhombic space group Pnma and orders magnetically at TN ≈ 90 K, two ...
Hung‐Cheng Wu, Yu‐Hsin Liao, Chih‐Chung Tsai, Pei‐Ying Yang, Yu‐Hao Chang, Yu‐Hui Liang, D. Chandrasekhar Kakarla, Ajay Tiwari, C. Dhanasekhar, Chin‐Wei Wang, Daisuke Okuyama, Chia‐Nung Kuo, Chin‐Shan Lue, Tzu‐Hsuan Weng, Kung‐Hsuan Lin, Jau‐Wern Chiou, Chi‐Hung Lee, Hung‐Duen Yang   +17 more
wiley   +1 more source

One-pot click synthesis of hybrid triazole–pyridine-functionalized polyphenol derivatives under ultrasound irradiation and their antimicrobial assays

Scientific Reports
In the present work, we describe an efficient, straightforward, and environmentally friendly method for synthesizing hybrid triazole-pyridine-functionalized polyphenol derivatives via a one-pot, three-component click reaction under ultrasound irradiation.
Dorina Amariucai-Mantu, Camelia-Georgiana Marandis, Dumitrela Diaconu, Vasilichia Antoci, Ionel I. Mangalagiu   +4 more
doaj   +1 more source