Results 171 to 180 of about 1,181,725 (347)

Targeting Decidual CD16+ Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage

Advanced Science, EarlyView.
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang, Zhinang Yin, Yanqiong Shen, Gang Feng, Fangfang Dai, Dongyong Yang, Zhimin Deng, Jing Yang, Ruizhi Chen, Leifeng Yang, Xian Chen, Qing Sun, Chunyu Huang, Yanxiang Cheng, Hongbing Deng, Lianghui Diao, Longfei Li, Tailang Yin   +17 more
wiley   +1 more source

Clicks2Line: Using Lines for Interactive Image Segmentation [PDF]

arXiv
For click-based interactive segmentation methods, reducing the number of clicks required to obtain a desired segmentation result is essential. Although recent click-based methods yield decent segmentation results, we observe that substantial amount of clicks are required to segment elongated regions.
arxiv  

New Methodology to Search for DNA Binding Ligands Based on Duplex DNA-Templated Click Chemistry [PDF]

, 2008
Shion Imoto, Tomoya Hirohama, Fumi Nagatsugi   +2 more
openalex   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

From Lab to Life: Self‐Powered Sweat Sensors and Their Future in Personal Health Monitoring

Advanced Science, EarlyView.
This review focuses on recent advances in self‐powered sweat sensors in personal health monitoring, including sweat sensors, energy harvesters, energy management, and their applications. It analyzes the difficulties and challenges in the research field of self‐powered sweat sensors and looks into the future direction of self‐powered sweat sensors from ...
Nan Gao, Guodong Xu, Gang Chang, Yuxiang Wu   +3 more
wiley   +1 more source

Convenient Approach to Access Octa-Glycosylated Porphyrins via “Click Chemistry” [PDF]

, 2009
Misako Okada, Yuko Kishibe, Kanako Ide, T. Takahashi, Teruaki Hasegawa   +4 more
openalex   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Alginate modification via click chemistry for biomedical applications.

Carbohydrate Polymers, 2021
Yaling Deng, A. Shavandi, O. Okoro, L. Nie   +3 more
semanticscholar   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui, Meng Yang, Chengli Yu, Haidong Zhang, Yuan Gong, Yang Hu, Yue Wang, Qingxin Yuan, An Pan, Jiepin Li, Yaowen Hu, Zecheng Jin, Xuemei Peng, Anyuan Wu, Junwei Wang, Qian Wang, Yinan Zhang, Lihong Hu   +17 more
wiley   +1 more source

Target Identification by Diazirine Photo‐Cross‐Linking and Click Chemistry [PDF]

, 2009
Andrew L. MacKinnon, Jack Taunton
openalex   +1 more source