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Click Chemistry

RCSB Protein Data Bank, 2022
Clickchemistry is a discipline that has developed rapidly over the past two decades. In this Thieme WebCheminar, Floris Rutjes (SOS Editor of ‘Click Chemistry’) and SOS authors Hannes Mikula and John Moses will discuss recent progress in click and bioorthogonal chemistry.
Hannes Mikula, John E. Moses
  +5 more sources

Light-Triggered Click Chemistry

Chemical Reviews, 2020
The merging of click chemistry with discrete photochemical processes has led to the creation of a new class of click reactions, collectively known as photoclick chemistry. These light-triggered click reactions allow the synthesis of diverse organic structures in a rapid and precise manner under mild conditions.
Gangam Srikanth Kumar, Qing Lin
openaire   +2 more sources

Click Chemistry with Polysaccharides

Macromolecular Rapid Communications, 2006
AbstractSummary: The copper‐catalyzed Huisgen reaction as a typical example of click chemistry was realized with the polysaccharide cellulose for the first time. The generality, selectivity, and the efficiency of click chemistry perfectly fit the requirements of polysaccharide modification, which is demonstrated by the introduction of triazole‐spacer ...
Liebert, T., Hänsch, C., Heinze, T.
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Click Chemistry with Ynamides.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maarten IJsselstijn   +1 more
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Thiol–Ene Click Chemistry

Angewandte Chemie International Edition, 2010
AbstractFollowing Sharpless′ visionary characterization of several idealized reactions as click reactions, the materials science and synthetic chemistry communities have pursued numerous routes toward the identification and implementation of these click reactions.
Hoyle, Charles E.   +1 more
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Ultrafast Click Chemistry with Fluorosydnones

Angewandte Chemie International Edition, 2016
AbstractWe report the synthesis and reactivity of 4‐fluorosydnones, a unique class of mesoionic dipoles displaying exquisite reactivity towards both copper‐catalyzed and strain‐promoted cycloaddition reactions with alkynes. Synthetic access to these new mesoionic compounds was granted by electrophilic fluorination of σ‐sydnone PdII precursors in the ...
Liu, Hui   +13 more
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Click Bioconjugation: Modifying Proteins Using Click‐Like Chemistry

ChemBioChem, 2022
AbstractBioconjugation deals with the chemical modification of proteins. The reactions used exploit either the intrinsic chemical reactivity of the biomolecule or introduce functionalities that can then be subsequently reacted without interfering with other functional groups of the biological entity.
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DNA Methyltransferase-Moderated Click Chemistry

Organic Letters, 2005
[reaction: see text]. Biological methylation plays a vital role in regulatory mechanisms of gene transcription. Methylation of both promoter sequences within the genome, as well as protein substrates, has a profound impact upon gene transcription. Yet, few tools exist by which to identify sites of biological methylation in complex biological mixtures ...
Rachel L, Weller, Scott R, Rajski
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Hydrogel‐Based Macroscopic Click Chemistry

Angewandte Chemie, 2023
AbstractThe click reaction has found good utility across various fields due to the characteristics of high efficiency, atom economy, simple and mild reaction conditions. Click chemistry is usually utilized for connecting components of microscopic level, while it is still unable for joining macroscopic building blocks.
Qingyun Li, Ziqing Hu, Xiaofan Ji
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Visible‐Light‐Induced Click Chemistry

Angewandte Chemie International Edition, 2015
AbstractA rapid and catalyst‐free cycloaddition system for visible‐light‐induced click chemistry is reported. A readily accessible photoreactive 2H‐azirine moiety was designed to absorb light at wavelengths above 400 nm. Irradiation with low‐energy light sources thus enables efficient small‐molecule synthesis with a diverse range of multiple‐bond ...
Mueller, Jan O.   +3 more
openaire   +3 more sources

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