Results 291 to 300 of about 328,516 (352)

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging. [PDF]

open access: yesArch Toxicol
Čadež T   +8 more
europepmc   +1 more source

Manipulation of Chemistry and Biology with Visible Light Using Tetra‐ortho‐Substituted Azobenzenes and Azonium Ions

open access: yesAngewandte Chemie, EarlyView.
Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano   +2 more
wiley   +1 more source

Stepwise virus assembly in the cell nucleus revealed by spatiotemporal click chemistry of DNA replication. [PDF]

open access: yesSci Adv
Gomez-Gonzalez A   +7 more
europepmc   +1 more source

A Photoactivatable Plasma Membrane Probe Based on a Self‐Triggered Photooxidation Cascade for Live Cell Super‐Resolution Microscopy

open access: yesAngewandte Chemie, EarlyView.
Herein, we establish a new photoswitching concept called self‐triggered photooxidation cascade (STPC). Rhodamine dyes have mild photosensitizing properties that enable subsequent photoactivation and photobleaching of a leuco‐rhodamine plasma membrane probe.
Sonia Pfister   +3 more
wiley   +1 more source

Click chemistry-based dual nanosystem for microRNA-122 detection with single-base specificity from tumour cells. [PDF]

open access: yesJ Nanobiotechnology
Robles-Remacho A   +10 more
europepmc   +1 more source

New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain

open access: yesAngewandte Chemie, EarlyView.
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song   +8 more
wiley   +1 more source

Development of Novel Immobilized Copper-Ligand Complex for Click Chemistry of Biomolecules. [PDF]

open access: yesMolecules
Kandler R   +7 more
europepmc   +1 more source

Ribozyme‐Catalyzed Site‐Specific Labeling of RNA Using O6‐alkylguanine SNAP‐Tag Substrates

open access: yesAngewandte Chemie, EarlyView.
SNAPR is a ribozyme that repurposes O6‐benzylguanine SNAP‐tag substrates for site‐specific labeling of RNA with bioorthogonal alkyne and azide functional groups, fluorophores or photocrosslinkers. The N1A‐alkylated RNA products were converted to N6A‐modified RNA by Dimroth rearrangement.
Manisha B. Walunj   +3 more
wiley   +1 more source

Click-Chemistry-Enabled Functionalization of Cellulose Nanocrystals with Single-Stranded DNA for Directed Assembly. [PDF]

open access: yesACS Biomater Sci Eng
Bukharina D   +9 more
europepmc   +1 more source

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