Results 141 to 150 of about 5,177,092 (374)

Prospects of click chemistry reactions in nuclear medicine: the TCO-Tz reaction based on the IEDDA mechanism

open access: yesNuclear Medicine Review
Click chemistry reactions, characterized by their high efficiency, strong selectivity, unique in vivo pre-targeting capabilities, and bioorthogonality, have shown great promise in nuclear medicine in recent years.
Yufeng Jing   +3 more
doaj   +1 more source

"Click" chemistry as a tool to create novel biomaterials: a short review

open access: yesU.Porto Journal of Engineering, 2015
In recent years, there has been a growing demand for novel strategies for biomedical applications. Chitosan is a typical cationic amino-containing polysaccharide that has been widely used due to its unique properties.
Mariana Barbosa   +2 more
doaj   +1 more source

Cupric oxide nanowires on three-dimensional copper foam for application in click reaction

open access: yes, 2017
Readily prepared CuO nanowires (CuO NWs) have been found to be effective heterogeneous catalysts for the 1,3-dipolar cycloaddition (CuAAC) reaction without using any additional support and bases.
Chunxia Wang   +5 more
semanticscholar   +1 more source

Visible light mediated metal-free thiol–yne click reaction

open access: yesChemical Science, 2016
Efficient metal-free photoredox pathway to the thiol–yne click reaction is described using Eosin Y as a catalyst and dedicated 3D-printed photoreactor.
Sergey S. Zalesskiy   +2 more
semanticscholar   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

IL‐2 Free Expansion of T Cells with Immunofilaments

open access: yesAdvanced Healthcare Materials, EarlyView.
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck   +4 more
wiley   +1 more source

Spatial attention shifting and phonological processing in adults with dyslexia [PDF]

open access: yes, 2015
According to Hari and Renvall’s (2001) sluggish attentional shifting (SAS) hypothesis people with dyslexia have a central deficit in attention shifting.
Abbott, I, Dunn, AK, Larkin, RF
core  

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

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