Results 51 to 60 of about 2,411,722 (343)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Journal of Advances in Modeling Earth Systems, 2018 Low clouds strongly impact the radiation budget of the climate system, but their simulation in most GCMs has remained a challenge, especially over the subtropical stratocumulus region.
Yi Qin +4 more
doaj +1 more source
Tellus: Series A, Dynamic Meteorology and Oceanography, 2022 Since the dawn of functioning numerical dynamical atmosphere- and ocean models, their resolution has steadily increased, fed by an exponential growth in computational capabilities.
Thorsten Mauritsen +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Desertification Mitigation in Northern China Was Promoted by Climate Drivers after 2000
Remote SensingDesertification greatly threatens the ecological environment and sustainable development over approximately 30% of global land. In this study, the contributions of climate drivers and human activity in shaping the desertification process from 1984 to ...
Haohui Li +6 more
doaj +1 more source
Cloud Computing for Climate Modelling: Evaluation, Challenges and Benefits
Computers, 2020 Cloud computing is a mature technology that has already shown benefits for a wide range of academic research domains that, in turn, utilize a wide range of application design models.
Diego Montes +5 more
doaj +1 more source
A framework for modeling uncertainty in regional climate change [PDF]
, 2015 In this study, we present a new modeling framework and a large ensemble of climate projections to investigate the uncertainty in regional climate change over the United States (US) associated with four dimensions of uncertainty.
Gao, X +4 more
core
Computational Methods for Parameter Estimation in Climate Models [PDF]
, 2008 Intensive computational methods have been used by Earth scientists in a wide range of problems in data inversion and uncertainty quantification such as earthquake epicenter location and climate projections.
Huerta, Gabriel +3 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The impact of Arctic sea ice loss on mid-Holocene climate. [PDF]
, 2018 Mid-Holocene climate was characterized by strong summer solar heating that decreased Arctic sea ice cover. Motivated by recent studies identifying Arctic sea ice loss as a key driver of future climate change, we separate the influences of Arctic sea ice ...
Kim, Seo-Yeon +5 more
core +2 more sources