Results 91 to 100 of about 471,024 (280)
Risk and Lifestyle Sports: The Case of Bouldering
Entertainment and Sports Law Journal, 2017 The recent case of Maylin v Dacorum Sports Trust [2017] EWHC 378 (QB) is the latest example of a claim being made for damages suffered whilst participating in bouldering, a form of low-level climbing.
Guy Osborn, Paul Gilchrist
doaj +2 more sources
Articulated elastic-loop roving vehicles [PDF]
, 1973 Prototype vehicle features exceptional obstacle-negotiating and slope-climbing capabilities plus high propulsive efficiency. Concept should interest designers of polar or ocean-bottom research vehicles.
Chang, C. J., Trautwein, W.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Embodied planning in climbing: how pre-planning informs motor execution
Frontiers in PsychologyIntroductionThe aim of the study is to address embodied planning in climbing. Embodied planning was conceptualized as the interaction between perceptual-cognitive pre-planning and motor execution.MethodsIn an experimental study, 18 climbers were asked to
Vicente Luis-del Campo +3 more
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Memory for the Functional Characteristics of Climbing Walls: Perceiving Affordances [PDF]
, 2002 M.S.J. Boschker +2 more
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Lean - Mean: Tree climbing machine! [PDF]
, 2018 Staying fit and healthy is essential if you are planning a long and productive climbing career. Keys to maintaining good fitness and health, along with treating injuries carefully will be discussed in this interactive session.
Harrison, Andrew
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Escape rooms: behavioural response of two invasive crayfish species under water decline scenarios
Journal of LimnologyClimate change and invasive alien species pose a significant threat to biodiversity and the survival of native species. This study considered the impact of drought conditions on the escape behaviour through terrestrial dispersal ability of two invasive ...
Daniela Ghia +3 more
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Dislocation climb driven by lattice diffusion and core diffusion
, 2023 Fengxian Liu +2 more
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