Results 51 to 60 of about 471,024 (280)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Jurnal Ilmiah Medicamento, 2016 Afrodisiaka adalah semua bahan baik obat dan makanan yang dapat membangkitkan gairah seksual. Di Indonesia terdapat begitu banyak bahan tanaman obat herbal alami yang dapat digunakan sebagai afrodisiaka.
Ketut Agus Adrianta +1 more
doaj +3 more sources
Frontiers in Sports and Active Living, 2022 Performance diagnostics of finger strength is very relevant in climbing. The aim of our study was to find modalities for an intermittent finger flexor muscle endurance test that optimize the correlation of test performance with lead climbing performance.
Claudia Augste +2 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Frontiers in Physiology, 2022 Background: Sport climbing places high mechanical loads on fingers. In 2012, our research group demonstrated adaptations of climbers’ cortical bones with the presence of osteophytes compared to non-climbing controls.Objectives: 1) To investigate 10-year ...
Torsten Pastor +8 more
doaj +1 more source
Moisture tempers impairment of adult Otiorhynchus sulcatus (Coleoptera: Curculionidae) climbing ability by fluoropolymer, talc dust, and lithium grease [PDF]
, 2005 As part of a project to develop tools for the physical exclusion of flightless root weevils, adult black vine weevils (BVW), Otiorhynchus sulcatus (F.), were placed in open enclosures with smooth walls of glass, plastic or aluminum to test their ability ...
Bomford, Michael K., Vernon, Robert S.
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
The (re)production of climbing space: bodies, gestures, texts [PDF]
, 2016 According to Lefebvre, space is not an absolute given, an empty and presumed starting point, but space is produced through human action. Further, he contends, there is a material basis to the production of space – the “practical and fleshy body”.
Rickly, J.M.
core +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
DigiWall - an audio mostly game [PDF]
, 2006 DigiWall is a hybrid between a climbing wall and a computer game. The climbing grips are equipped with touch sensors and lights. The interface has no computer screen. Instead sound and music are principle drivers of DigiWall interaction models.
Liljedahl, Mats, Lindberg, Stefan
core