Results 21 to 30 of about 67,961 (278)

Understanding and Addressing CLSI Breakpoint Revisions: a Primer for Clinical Laboratories [PDF]

Journal of Clinical Microbiology, 2019
The Clinical and Laboratory Standards Institute (CLSI) has revised several breakpoints since 2010 for bacteria that grow aerobically. In 2019, these revisions include changes to the ciprofloxacin and levofloxacin breakpoints for the Enterobacteriaceae and Pseudomonas aeruginosa , daptomycin ...
Romney M, Humphries, April N, Abbott, Janet A, Hindler   +2 more
openaire   +2 more sources

Cephalexin susceptibility breakpoint for veterinary isolates: Clinical Laboratory Standards Institute revision [PDF]

Journal of Veterinary Diagnostic Investigation, 2017
The Clinical and Laboratory Standards Institute (CLSI) uses cephalothin as the class representative for testing veterinary isolates for susceptibility to other first-generation cephalosporins, including cephalexin. We examined replacing cephalothin with cephalexin because cephalexin is used more often clinically.
Mark G, Papich, Cindy, Lindeman
openaire   +2 more sources

Reliability analysis of exonic-breakpoint fusions identified by DNA sequencing for predicting the efficacy of targeted therapy in non-small cell lung cancer

BMC Medicine, 2022
Background Diverse genomic breakpoints of fusions that localize to intronic, exonic, or intergenic regions have been identified by DNA next-generation sequencing (NGS), but the role of exonic breakpoints remains elusive.
Weihua Li, Rui Wan, Lei Guo, Geyun Chang, Dong Jiang, Lin Meng, Jianming Ying   +6 more
doaj   +1 more source

Long-Read Sequencing Revealed Extragenic and Intragenic Duplications of Exons 56–61 in DMD in an Asymptomatic Male and a DMD Patient

Frontiers in Genetics, 2022
Expanded carrier screening (ECS) has become an increasingly common technique to assess the genetic risks of individuals in the prenatal or preconception period.
Ying Bai, Ju Liu, Jinghan Xu, Yue Sun, Jingjing Li, Yong Gao, Lina Liu, Cangcang Jia, Xiangdong Kong, Li Wang   +9 more
doaj   +1 more source

Pharmacodynamic Thresholds for Beta-Lactam Antibiotics: A Story of Mouse Versus Man

Frontiers in Pharmacology, 2022
Beta-lactams remain a critical member of our antibiotic armamentarium and are among the most commonly prescribed antibiotic classes in the inpatient setting.
Angela V. Berry, Joseph L. Kuti
doaj   +1 more source

IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia [PDF]

, 2019
IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in both childhood and adult B-cell precursor acute lymphoblastic leukemia (B-ALL). Previously, we revealed that COBL is a hotspot for breakpoints in leukemia and could promote IKZF1 deletions ...
Alonso, Cristina N., Bakhshi, Sameer, Barbosa, Thayana C., Bashton, Matthew, Cazzaniga, Gianni, Duployez, Nicolas, Emerenciano, Mariana, Gupta, Sanjeev K., Harrison, Christine J., Horstmann, Martin, Lopes, Bruno A., Mansur, Marcela B., Marschalek, Rolf, Meyer, Claus, Palmi, Chiara, Pombo-de-Oliveira, Maria S., Poubel, Caroline P., Sutton, Rosemary, Tsaur, Grigory, Venn, Nicola C., zur Stadt, Udo   +20 more
core   +1 more source

Clinical breakpoint meropenem concentration modulate outer membrane vesicle production in enterotoxigenic Bacteroides fragilis. [PDF]

Arch Microbiol
Kozhakhmetova S, Bekbayeva A, Zholdybayeva E, Krivoruchko T, Dashevskaya N, Vinogradova E, Kamzayeva N, Khassenbekova Z, Kushugulova A, Kozhakhmetov S.   +9 more
europepmc   +2 more sources

Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days [PDF]

, 2009
Structural chromosome aberrations and associated segmental or chromosomal aneusomies are major causes of reproductive failure in humans. Despite the fact that carriers of reciprocal balanced translocation often have no other clinical symptoms or ...
Baumgartner, Adolf, Escudero, Tomas, Kwan, Johnson, Lu, Chun-Mei, Munné, Santiago, Wang, Mei, Weier, Heinz-Ulrich G., Weier, Jingly F.   +7 more
core   +2 more sources

The Precise Breakpoint Mapping in Paracentric Inversion 10q22.2q23.3 by Comprehensive Cytogenomic Analysis, Multicolor Banding, and Single-Copy Chromosome Sequencing

Biomedicines, 2022
Detection and precise genomic mapping of balanced chromosomal abnormalities in patients with impaired fertility or a clinical phenotype represent a challenge for current cytogenomics owing to difficulties with precise breakpoint localization in the ...
Tatyana V. Karamysheva, Tatyana A. Gayner, Eugeny A. Elisaphenko, Vladimir A. Trifonov, Elvira G. Zakirova, Konstantin E. Orishchenko, Mariya A. Prokhorovich, Maria E. Lopatkina, Nikolay A. Skryabin, Igor N. Lebedev, Nikolay B. Rubtsov   +10 more
doaj   +1 more source

Growth in Public Interest and Scientific Research on Kinesiology Taping [PDF]

, 2018
Kinesiology taping has grown in popularity, though there are a number of unsubstantiated claims made by some kinesiology taping advocates. An investigation was conducted into trends in general and scientific interest in kinesiology taping.
Climstein, Michael, Furness, James, Heazlewood, Ian Timothy, Perin, Jason Daniel, Qureshi, Hassan Ghani, Rahman, Haseeb, Walsh, Joe, Walsh, Tom   +7 more
core   +1 more source