Results 21 to 30 of about 5,362,679 (291)

Long-Read Sequencing Revealed Extragenic and Intragenic Duplications of Exons 56–61 in DMD in an Asymptomatic Male and a DMD Patient

Frontiers in Genetics, 2022
Expanded carrier screening (ECS) has become an increasingly common technique to assess the genetic risks of individuals in the prenatal or preconception period.
Ying Bai, Ju Liu, Jinghan Xu, Yue Sun, Jingjing Li, Yong Gao, Lina Liu, Cangcang Jia, Xiangdong Kong, Li Wang   +9 more
doaj   +1 more source

Pharmacodynamic Thresholds for Beta-Lactam Antibiotics: A Story of Mouse Versus Man

Frontiers in Pharmacology, 2022
Beta-lactams remain a critical member of our antibiotic armamentarium and are among the most commonly prescribed antibiotic classes in the inpatient setting.
Angela V. Berry, Joseph L. Kuti
doaj   +1 more source

Breakpoint graph of digital finance.

, 2023
(A) Breakpoint graph of DIF. (B) Breakpoint graph of DIF_COVER. (C) Breakpoint graph of DIF_USAGE. (D) Breakpoint graph of DIF_DIGIT.
Tao Cen (15242987), Qiaoyun Wu (17419771), Liya Zheng (4792533)   +2 more
core   +1 more source

Establishing Antimicrobial Susceptibility Testing Methods and Clinical Breakpoints for Inhaled Antibiotic Therapy [PDF]

Open Forum Infectious Diseases, 2022
Abstract Inhaled antibiotics are a common and valuable therapy for patients suffering from chronic lung infection, with this particularly well demonstrated for patients with cystic fibrosis. However, in vitro tests to predict patient response to inhaled antibiotic therapy are currently lacking.
Miquel B Ekkelenkamp, María Díez-Aguilar, Michael M Tunney, J Stuart Elborn, Ad C Fluit, Rafael Cantón   +5 more
openaire   +4 more sources

MCG&BA‐Net: Retinal vessel segmentation using multiscale context gating and breakpoint attention

IET Image Processing, 2022
The accurate segmentation of blood vessels plays a crucial role in screening, diagnosis and treatment of multiple diseases. However, current automated segmentation approaches do not pay enough attention to the vascular topology errors (such as mistaking ...
Pengfei Xu, Gangjing Zhao, Jinping Liu, Hadi Jahanshahi, Zhaohui Tang, Subo Gong   +5 more
doaj   +1 more source

The Precise Breakpoint Mapping in Paracentric Inversion 10q22.2q23.3 by Comprehensive Cytogenomic Analysis, Multicolor Banding, and Single-Copy Chromosome Sequencing

Biomedicines, 2022
Detection and precise genomic mapping of balanced chromosomal abnormalities in patients with impaired fertility or a clinical phenotype represent a challenge for current cytogenomics owing to difficulties with precise breakpoint localization in the ...
Tatyana V. Karamysheva, Tatyana A. Gayner, Eugeny A. Elisaphenko, Vladimir A. Trifonov, Elvira G. Zakirova, Konstantin E. Orishchenko, Mariya A. Prokhorovich, Maria E. Lopatkina, Nikolay A. Skryabin, Igor N. Lebedev, Nikolay B. Rubtsov   +10 more
doaj   +1 more source

Principles of genome evolution in the Drosophila melanogaster species group. [PDF]

, 2007
That closely related species often differ by chromosomal inversions was discovered by Sturtevant and Plunkett in 1926. Our knowledge of how these inversions originate is still very limited, although a prevailing view is that they are facilitated by ...
Marcin von Grotthuss, Yuk S Chan, José M Ranz, Damien Maurin, Michael Ashburner, Casey M Bergman, LaDeana W Hillier, John Roote, Chan Yuk S, Bergman Casey M, Bergman, Casey, Hillier LaDeana W, Ranz, JM, Hillier, LaDeana W., Ashurner, M, Von Grotthuss, M, Roote, John, Chan, YS, Ranz José M, Ashburner Michael, von Grotthuss Marcin, Maurin Damien, Roote John, Bergman, C. M, Maurin, D   +24 more
core   +2 more sources

Clinical Impact of Revised Cefepime Breakpoint in Patients With Enterobacteriaceae Bacteremia

Open Forum Infectious Diseases, 2019
Abstract The impact of the revised Clinical and Laboratory Standards Institute interpretative criteria for cefepime in Enterobacteriaceae remains unclear. We applied the new breakpoint on 644 previously defined cefepime-susceptible Enterobacteriaceae isolates. We found no differences in mortality or microbiological failure, regardless of
Kap Sum Foong, Abigail L Carlson, Satish Munigala, Carey-Ann D Burnham, David K Warren   +4 more
openaire   +3 more sources

The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach [PDF]

Clinical Microbiology and Infection, 2012
Clinical breakpoints are used in clinical microbiology laboratories to categorize microorganisms as clinically susceptible (S), intermediate (I) or resistant (R) dependent on the quantitative antimicrobial susceptibility as indicated by the MIC value determined in a well-defined standard test system. The laboratory report, with the designations of S, I
Mouton, J.W., Brown, D.F., Apfalter, P., Canton, R., Giske, C.G., Ivanova, M., MacGowan, A.P., Rodloff, A., Soussy, C.J., Steinbakk, M., Kahlmeter, G.   +10 more
openaire   +3 more sources

A proposal of clinical breakpoints for amoxicillin applicable to porcine respiratory tract pathogens [PDF]

Veterinary Microbiology, 2008
In the present position paper, an attempt was made to establish clinical breakpoints of amoxicillin to classify porcine respiratory tract pathogens as susceptible, intermediate or resistant based on their minimum inhibitory concentrations of amoxicillin.
Stefan, Schwarz, Alexander, Böttner, Luc, Goossens, Luc, Goosens, H Mohamed, Hafez, Katrin, Hartmann, Martin, Kaske, Corinna, Kehrenberg, Manfred, Kietzmann, Dieter, Klarmann, Günter, Klein, Peter, Krabisch, Gabriele, Luhofer, Angelika, Richter, Bianka, Schulz, Claudia, Sigge, Karl-Heinz, Waldmann, Jürgen, Wallmann, Christiane, Werckenthin   +18 more
openaire   +3 more sources