Results 191 to 200 of about 579,638 (359)

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

open access: yesAdvanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei   +10 more
wiley   +1 more source

ACCF/AHA/SCAI 2007 Update of the Clinical Competence Statement on Cardiac Interventional Procedures [PDF]

open access: bronze, 2007
Spencer B. King   +17 more
openalex   +1 more source

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Rationally Designed TadA‐Derived Cytosine Editors Enable Context‐Independent Zebrafish Genome Editing

open access: yesAdvanced Science, EarlyView.
A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin   +7 more
wiley   +1 more source

Self-Perceived Clinical Competence of Nurses in Different Working Experiences: A Cross-Sectional Study. [PDF]

open access: yesHealthcare (Basel), 2023
Notarnicola I   +16 more
europepmc   +1 more source

A Pilot Study to Evaluate Clinical Competence in Junior Grade Pharmacy Practitioners

open access: gold, 2003
G. H. Goldsmith   +6 more
openalex   +1 more source

From competence to capability: a study of nurse practitioners in clinical practice [PDF]

open access: green, 2007
Anne Gardner   +4 more
openalex   +1 more source

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