Results 31 to 40 of about 200,357 (333)

Sample size calculation based on the difference in restricted mean time lost for clinical trials with competing risks [PDF]

open access: yesarXiv, 2023
Computation of sample size is important when designing clinical trials. The presence of competing risks makes the design of clinical trials with time-to-event endpoints cumbersome. A model based on the subdistribution hazard ratio (SHR) is commonly used for trials under competing risks.
arxiv  

Pharmacokinetics of anti-infective agents during CytoSorb hemoadsorption

open access: yesScientific Reports, 2021
Cytokine hemoadsorption might be beneficial in patients with sepsis. However, its effect on anti-infective agents' disposition remains largely unknown.
Antoine G. Schneider   +6 more
doaj   +1 more source

The use of restricted mean time lost under competing risks data [PDF]

open access: yesBMC Medical Research Methodology 2020. 20:197, 2020
Background: Under competing risks, the commonly used sub-distribution hazard ratio (SHR) is not easy to interpret clinically and is valid only under the proportional sub-distribution hazard (SDH) assumption. This paper introduces an alternative statistical measure: the restricted mean time lost (RMTL).
arxiv   +1 more source

Similarity of competing risks models with constant intensities in an application to clinical healthcare pathways involving prostate cancer surgery [PDF]

open access: yesarXiv, 2021
The recent availability of routine medical data, especially in a university-clinical context, may enable the discovery of typical healthcare pathways, i.e., typical temporal sequences of clinical interventions or hospital readmissions. However, such pathways are heterogeneous in a large provider such as a university hospital, and it is important to ...
arxiv  

Causal inference with recurrent and competing events [PDF]

open access: yes, 2022
Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in athletes. Competing events, such as death, complicate causal inference in studies of recurrent events
arxiv   +1 more source

Economic stress and condescending treatment in childhood and adult self-rated health: results from a population study in Sweden

open access: yesBMC Public Health, 2017
Background Even today, 12% of the children in Sweden live in poverty and many children are exposed to adverse experiences, such as being bullied, which may have long-term consequences on public health.
Fredrik Granström   +2 more
doaj   +1 more source

An analysis of the relationship between resilience and clinical competence in nurses: A descriptive-correlational study

open access: yesChristian Journal for Global Health, 2022
Objective: Resilience and clinical competence are two important components of providing nursing care to patients. The goal was to determine the correlation between clinical competence and resilience in the nurses at Babol University of Medical Sciences ...
Parvin Aziznejadroshan   +5 more
doaj   +1 more source

Competences of Clinical Psychologists

open access: yesClinical Psychology in Europe, 2019
Politicians, societies, stakeholders, health care systems, patients, their relatives, their employers, and the general population need to know what they can expect from clinical psychologists. Even more, for our self-definition as a professional group, we should share a common understanding of the competence profile that characterises our ...
openaire   +3 more sources

Is nurses’ clinical competence associated with their compassion satisfaction, burnout and secondary traumatic stress? A cross‐sectional study

open access: yesNursing Open, 2021
Aim The current study aimed to investigate the relationship between clinical competence and subscale of professional quality of life (ProQOL). Methods This cross‐sectional study was conducted from November 2018 to May 2019 on 291 nurses working in public
Mohammad Ali Zakeri   +6 more
doaj   +1 more source

Pilot study of safety and efficacy of polyprenols in combination with coenzyme Q10 in patients with statin-induced myopathy

open access: yesMedicina, 2016
Background and objective: Statin-induced myopathy (SIM) has been partially attributed to deficiency of dolichol and coenzyme Q10 (CoQ10). We aimed to test the safety and efficacy of plant polyprenols in combination with CoQ10 for alleviation of SIM ...
Gustavs Latkovskis   +6 more
doaj   +1 more source

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