Results 51 to 60 of about 198,253 (268)

Paracrine- and cell-contact-mediated immunomodulatory effects of human periodontal ligament-derived mesenchymal stromal cells on CD4+ T lymphocytes

Stem Cell Research & Therapy
Background Mesenchymal stromal cells (MSCs) isolated from the periodontal ligament (hPDL-MSCs) have a high therapeutic potential, presumably due to their immunomodulatory properties.
Christian Behm, Oliwia Miłek, Xiaohui Rausch-Fan, Andreas Moritz, Oleh Andrukhov   +4 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Treatment outcomes, symptoms of anxiety and depression, and satisfaction with life after orthognathic surgery

Frontiers in Oral Health
BackgroundPsychological factors may affect surgical outcomes. This study aimed to evaluate the treatment results of orthognathic surgery, and to investigate how anxiety, depression and satisfaction with life affect overall patient satisfaction ...
Kine Jespersen, Thomas Brox, Thomas Brox, Sølve Hellem, Bo Wold Nilsen, Bo Wold Nilsen, Ellen Nordal, Ellen Nordal, Jan-Are K. Johnsen, Sigurd Hadler-Olsen, Paula Frid, Paula Frid, Paula Frid   +12 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

A comparative study of the epithelial regeneration capacities of two biomaterials in vitro

BMC Oral Health
Background Regeneration of periodontal epithelium remains a major focus in current dental research, with various exogenous substitute materials being applied in clinical practice.
Zhiwei Tian, Zhongqi Zhao, Marco Aoqi Rausch, Christian Behm, Dino Tur, Hassan Ali Shokoohi-Tabrizi, Oleh Andrukhov, Xiaohui Rausch‑Fan   +7 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

ExplORRNet: An interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers

Non-coding RNA Research
Background: MicroRNAs (miRNAs) are key regulators of gene expression that have been implicated in gynecological and breast cancers. Understanding the cancer stage-wise expression patterns of miRNAs and their interactions with other RNA molecules in ...
Ankita Lawarde, Edris Sharif Rahmani, Adhiraj Nath, Darja Lavogina, Jana Jaal, Andres Salumets, Vijayachitra Modhukur   +6 more
doaj   +1 more source

Prevalence of Parasomnias in Patients With Obstructive Sleep Apnea. A Registry-Based Cross-Sectional Study

Frontiers in Psychology, 2018
Objective: To assess the prevalence of parasomnias in relation to presence and severity of obstructive sleep apnea (OSA). We hypothesized higher parasomnia prevalence with higher OSA severity.Methods: The sample comprised 4,372 patients referred to a ...
Ragnhild S. Lundetræ, Ingvild W. Saxvig, Ståle Pallesen, Ståle Pallesen, Harald Aurlien, Harald Aurlien, Sverre Lehmann, Sverre Lehmann, Bjørn Bjorvatn, Bjørn Bjorvatn   +9 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Evaluation of clinical competence and its related factors among ICU nurses in Kermanshah-Iran: A cross-sectional study

International Journal of Nursing Sciences, 2019
Objectives: The present study was conducted to evaluate the clinical competence and its related demographic factors among critical care nurses in Kermanshah, Iran.
Azam Faraji, Mahtab Karimi, Seyyed Mohsen Azizi, Maryam Janatolmakan, Alireza Khatony   +4 more
doaj   +1 more source