Results 31 to 40 of about 6,050,070 (254)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Cultural competence versus ‘clinical tourism’

open access: yes, 2010
Cultural competence versus 'clinical tourism' Background: Nursing practice in Australia requires that students have a sound understanding of cultural awareness, sensitivity and safety which form the underpinning of most nursing curricula ...
Rands, Hazel, Emmanuel, Elizabeth
core  

PROFESSIONAL COMPETENCE OF BORDER GUARDS IN THE REPUBLIC OF INDIA [PDF]

open access: yes, 2018
On the basis of analysis of scientific pedagogical literature we have investigated the notions of «professional competence» and «professional military competence», also defined the category of professional competence of border guards in the Republic of ...
Bhinder, N. V., N. V. Bhinder
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Clinical Reasoning as a Core Competency

open access: yesAcademic Medicine, 2019
Diagnostic error is a challenging problem; addressing it effectively will require innovation across multiple domains of health care, including medical education. Diagnostic errors often relate to problems with clinical reasoning, which involves the cognitive and relational steps up to and including establishing a diagnostic and therapeutic plan with a ...
Denise M, Connor   +2 more
openaire   +3 more sources

Occupational therapy essentials for clinical competence

open access: yes, 2017
Occupation, theory-driven, evidence-based, and client-centered practice continue to be the core of the profession and is the central focus of Occupational Therapy Essentials for Clinical Competence, Third Edition.
Jacobs, Karen 1951-, MacRae, Nancy 1944-
core  

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

open access: yesFEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki   +5 more
wiley   +1 more source

'Video-View-Point' - Video analysis to reveal tacit indicators of student nurse competence

open access: yes, 2014
For over 30 years, the assessment of the clinical competence of student nurses has been the subject of much theoretical debate, yet the definition of criteria based on observable indicators of competence remains problematic.
Monger, Eloise
core   +1 more source

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