Results 81 to 90 of about 186,308 (246)

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Feasibility of a pioneer social service treatment for gambling disorder—The first 6-month follow-up data

Emerging Trends in Drugs, Addictions, and Health
Gambling disorder can be treated with cognitive behavioral therapy (CBT), but treatment is under-dimensioned in many settings. For example, in Sweden, a setting with mixed responsibility for addiction treatment between health care and social services ...
C. Grudet, G. Åkesson, K. Wennerstrand, A. Håkansson   +3 more
doaj   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Impact of Zirconia and Titanium Implant Surfaces of Different Roughness on Oral Epithelial Cells

Dentistry Journal
Background/Objectives: Formation of tight contacts between oral soft tissue and dental implants is a significant challenge in contemporary implantology. An essential role in this process is played by oral epithelial cells.
Marco Aoqi Rausch, Zhiwei Tian, Vera Maierhofer, Christian Behm, Christian Ulm, Erwin Jonke, Raphael S. Wagner, Benjamin E. Pippenger, Bin Shi, Xiaohui Rausch-Fan, Oleh Andrukhov   +10 more
doaj   +1 more source

The Study of critical thinking disposition, clinical competence, and satisfaction of clinical practice in nursing students [PDF]

, 2019
Jin Ju Yang
openalex   +1 more source

Therapist competence and clinical outcome in the rehabilitation of memory following traumatic brain injury trial

, 2021
Emma Trigg, Sara Clarke, Dana Wong, Roshan das Nair   +3 more
openalex   +2 more sources

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Antibiotic prescription errors: the relationship with clinical competence in junior medical residents [PDF]

, 2022
Joshua Martínez-Domínguez, Octavio Sierra-Martínez, Arturo Galindo‐Fraga, Juan Andrés Trejo-Mejía, Melchor Sánchez Mendiola, Eric Ochoa‐Hein, Mirella Vázquez-Rivera, Carlos Gutiérrez‐Cirlos, Jesús Naveja, Adrián Martínez-González   +9 more
openalex   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

The objective structured clinical examination as an assessment strategy for clinical competence in novice nursing practitioners in Taiwan [PDF]

, 2021
Sue‐Hsien Chen, Shu-Ching Chen, Yo‐Ping Lai, Pin‐Hsuan Chen, Kun‐Yun Yeh   +4 more
openalex   +1 more source