Results 101 to 110 of about 5,531,484 (250)

The Value of Clinical Judgment in the Detection of Clinical Deterioration [PDF]

JAMA Internal Medicine, 2015
Amitkumar R, Patel, Frank J, Zadravecz, Robert S, Young, Mark V, Williams, Matthew M, Churpek, Dana P, Edelson   +5 more
openaire   +2 more sources

Unobtrusive Monitoring of Clinical Deterioration in Smart Homes

Clinical deterioration (CD) is the physiological decompensation that incurs care escalation, protracted hospital stays, or even death. The early warning score (EWS) calculates the occurrence of CD based on five vital signs. However, there are limited reports regarding EWS monitoring in smart home settings.
Sharareh Rostam Niakan Kalhori, Mozhgan Tanhapour, Thomas M. Deserno   +2 more
openaire   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Clinical Psychology Today Vol 4 Issue 2 (Winter 2020)

, 2020
Winter 2020 edition of Clinical Psychology Today journal. Includes articles on: Reflecting on Clinical Training During a Pandemic. The Evolution of Self-Care: From Explicit Techniques to Implicit Awareness An Exploration of Body-Centred ...
Collins (Series Editor), Padraig, McHugh (Edition Editor), Patrick, Wilson (Edition Editor), Charlotte   +2 more
core  

Clinical Profile of Patients Treated by the Rapid Response Team in a High-Complexity Institution in Eastern Antioquia: A Descriptive Study

Iatreia
Introduction: Rapid response teams use protocols to monitor patients with clinical deterioration and prevent in-hospital deaths. Objective: To describe the clinical profile of patients for whom the rapid response team is activated in a high-complexity
Arenas-Sierra, María Paula, Porto-Jaramillo, Yolima, Ávila-Sánchez, Oswaldo Andrés, Naranjo-Sánchez, Astrid Carolina, Ochoa-Vargas, Gisella, Herrera-Vargas, Jhojan Sebastián, Loaiza-Castaño, Jorge Mario   +6 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Clinical deterioration after sildenafil cessation in patients with pulmonary hypertension

, 2008
Anne M Keogh, Andrew Jabbour, Christopher S Hayward, Peter S MacdonaldHeart Lung Transplant Unit, St Vincent’s Hospital, Sydney, New South Wales, AustraliaAbstract: Sildenafil is a selective inhibitor of phosphodiesterase type 5 (PDE-5).
Peter S Macdonald, Christopher S Hayward, Anne M Keogh, Andrew Jabbour   +3 more
core  

Structural Deterioration Detection Using Enhanced Autoregressive Residuals [PDF]

, 2018
This paper presents a study on detecting structural deterioration in existing buildings using ambient vibration measurements. Deterioration is a slow and progressive process which reduces the structural performance, including load-bearing capacity.
Monavari, Benyamin, Nguyen, Andy, Chan, Tommy H. T., Thambiratnam, David P.   +3 more
core   +1 more source

How Few Sensors Are Enough? Minimum Vital Sign Requirements for ML-Based Deterioration Prediction

IEEE Access
Machine learning deterioration-prediction models typically require dozens of parameters; whether wearable-grade sensor sets suffice is unexplored. We identified the minimum vital sign configuration for in-hospital mortality prediction using MIMIC-IV (n ...
Yurii Myroshnyk, Oleksandr Leshchenko
doaj   +1 more source