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Finerenone: Extending MRAs Prognostic Benefit to the Recently Hospitalized and More Symptomatic Patient with HFpEF. [PDF]
Tinti MD +20 more
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Digital Tinnitus Counseling in Clinical Practice: A Multicenter Randomized Controlled Trial. [PDF]
Brueggemann P +3 more
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Capturing durable benefits: interpreting six-year treatment-free survival and restricted mean survival time in CheckMate 227. [PDF]
Kobayashi T, Nakamura S, Hakozaki T.
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Endpoint adjudication in cardiovascular clinical trials
European Heart Journal, 2023Abstract Endpoint adjudication (EA) is a common feature of contemporary randomized controlled trials (RCTs) in cardiovascular medicine. Endpoint adjudication refers to a process wherein a group of expert reviewers, known as the clinical endpoint committee (CEC), verify potential endpoints identified by site investigators. Events that are
Muhammad Shahzeb Khan +8 more
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Economic endpoints in clinical trials
Statistical Methods in Medical Research, 2004Healthcare decision makers are increasingly requesting information on the cost and cost-effectiveness of new medicines at the time of product launch. In order to provide this information, data on healthcare resource utilization and, in some cases, costs, may be collected in clinical trials.
Cook, John +2 more
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Composite Endpoints in Clinical Trials
Revista Española de Cardiología (English Edition), 2008Composite endpoints are often used in clinical trials, especially in the cardiovascular area. Decreases in sample size requirements, ability to assess the net effect of an intervention and to avoid bias in presence of competing risk are the most cited advantages for their use.
Ignacio, Ferreira-González +7 more
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