Results 311 to 320 of about 583,827 (328)

Clinical Endpoint Bioequivalence Study

2014
The goal of the clinical endpoint bioequivalence study is to perform a comparison of clinical effects of a test and reference drug in order to infer bioequivalence. The clinical endpoint bioequivalence study is a complex compromise method of determining bioequivalence of products that cannot be evaluated by means of a pharmacokinetic or pharmacodynamic
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Surrogate Endpoints in Clinical Trials

Drug Information Journal, 1996
Surrogate endpoints are used to document treatment effects more easily and rapidly, yet controversies arise in their use.
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Clinical Trials: New Endpoints

1999
Background. The Western community is currently increasingly involved in the problems of patients with chronic diseases. The wish to deal with such problems gives rise to new endpoints in medical research.
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[Intermediate endpoints in clinical research].

Nederlands tijdschrift voor geneeskunde, 2014
An intermediate variable such as blood pressure is part of the causal pathway of mechanisms to a clinical outcome, e.g. myocardial infarction. An intervention affects a clinical outcome through its effect on that intermediate variable. In studies designed to assess the effects of interventions an intermediate variable may be used as surrogate for ...
Sanne A E, Peters, Rolf H H, Groenwold, Michiel L, Bots   +2 more
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Clinical Endpoints

2009
Shruti, Sonni, Karen, Furie
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Composite endpoints in clinical trials

Οι κλινικές δοκιμές αποτελούν μια θεμελιώδη διαδικασία για την αξιολόγηση της αποτελεσματικότητας νέων θεραπειών. Ωστόσο, σε πολλές περιπτώσεις, ένα μόνο πρωτεύον τελικό σημείο δεν επαρκεί για την πλήρη καταγραφή του θεραπευτικού οφέλους, ειδικά όταν τα κλινικά συμβάντα είναι σπάνια, απαιτούν παρατεταμένη παρακολούθηση ή αποτυπώνουν μόνο ένα μέρος του ...
Kanellakopoulou, Adamantia, Kanellakopoulou, Adamantia   +1 more
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Clinical Endpoint

2003
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Surrogate endpoints in clinical trials

Controlled Clinical Trials, 1985
Lawrence Friedman, Salim Yusuf
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Compound endpoints in clinical trials

Controlled Clinical Trials, 1986
Michael Terrin, Sandra Forman
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Endpoints for Cancer Clinical Trials

2016
Pang, HMH, Wang, X, George, S
openaire   +3 more sources