Clinical Evaluation of a Novel Stool Antigen Test Using Bioluminescent Enzyme Immunoassay for Detecting Helicobacter pylori [PDF]
Canadian Journal of Gastroenterology and Hepatology, 2022 Background. BLEIA ™ “EIKEN” Helicobacter pylori antigen (B[EIA]) is based on the bioluminescent enzyme immunoassay (BLEIA) method that was newly developed with high sensitivity in detecting Helicobacter pylori (H. pylori) antigen in feces. Methods. In the project for H.
Toshihiko Kakiuchi +3 more
openalex +4 more sources
Radical-mediated Electrical Enzyme Assay For At-home Clinical Test [PDF]
To meet the growing demand for accurate, rapid, and cost-effective at-home clinical testing, we developed a radical-mediated enzyme assay (REEA) integrated with a paper fluidic system and electrically read by a handheld field-effect transistor (FET) device. The REEA utilizes horseradish peroxidase (HRP) to catalyze the conversion of aromatic substrates
Hyun‐June Jang +11 more
openalex +3 more sources
Clinical Specificity of the Enzyme Immunoassay Test for Coccidioidomycosis Varies According to the Reason for Its Performance [PDF]
Clinical and Vaccine Immunology, 2012 ABSTRACT The diagnosis of coccidioidomycosis relies heavily on serologic test results in addition to clinical history, physical examination, and radiographic findings. Use of the enzyme immunoassay (EIA) has increased because it is rapidly performed and does not require referral to a reference laboratory, as do complement fixation and ...
Janis E. Blair +4 more
openalex +3 more sources
, 2021 ABSTRACTBackgroundSerological testing for SARS-CoV-2 complements nucleic acid tests for patient diagnosis and enables monitoring of population susceptibility to inform the COVID-19 pandemic response. As we move into the era of vaccines, the detection of neutralising antibody will become increasingly important. Many serological tests have been developed
Suellen Nicholson +12 more
openalex +3 more sources
New perspectives for use of gamma-glutamyltranspeptidase in clinical enzymes tests
The Scientific Notes of the I. P. Pavlov St. Petersburg State Medical University, 2016 Gamma-glutamyltranspeptidase (GGTP), isolated from a variety of sources from microorganisms to mammals, including human blood and organs, has been studied sufficiently detailed, which allowed to take a fresh look at the role of this enzyme in cellular metabolism, the pathogenesis of several diseases and its application in clinical medicine.
L. А. Alexandrova
openalex +5 more sources
Clinical Correlation of a Clostridium difficile Testing Algorithm Reflexing PCR Positive Specimens to Toxin Enzyme Immunoassay (EIA) [PDF]
Open Forum Infectious Diseases, 2017 Abstract Background An algorithm promoted in the United Kingdom reflexes specimens positive for C. difficile by a nucleic acid amplification test (NAAT) to toxin EIA. Samples positive by NAAT and negative by toxin EIA are reported as “C. difficile could be present (ie, potential C. difficile excretor).
Maria Bueno Rios +5 more
openalex +3 more sources
The Physiological Sources of, Clinical Significance of, and Laboratory-Testing Methods for Determining Enzyme Levels [PDF]
Laboratory Medicine, 2014 Enzymes are organic molecules that accelerate biochemical reactions but emerge from the reaction unchanged. Abnormal levels of plasma enzymes are highly suggestive of damaged cells and provide clues to parts of the body that may be involved in disease processes. Enzyme levels are measured in the clinical laboratory to identify the site of damage and to
Muneeza Esani
openalex +3 more sources
Rapid Detection of Staphylococcus aureus Panton-Valentine Leukocidin in Clinical Specimens by Enzyme-Linked Immunosorbent Assay and Immunochromatographic Tests [PDF]
Journal of Clinical Microbiology, 2010 ABSTRACT Staphylococcus aureus strains producing Panton-Valentine leukocidin (PVL) have been epidemiologically linked to specific human infections. To evaluate immunological tests that may be used to diagnose infections with PVL-producing strains, we prospectively collected pus, respiratory tract specimens, and joint ...
Cédric Badiou +16 more
openalex +6 more sources
Genetic Testing for Enzymes of Drug Metabolism: Does It Have Clinical Utility for Pain Medicine at the Present Time? A Structured Review [PDF]
Pain Medicine, 2004 This is a structured review of genomic (genetic) testing for enzymes of drug metabolism.Recently, industry began offering genomic testing for enzymes of drug metabolism. As such, the objective of this review was to determine if genomic testing for enzymes of drug metabolism has any imminent clinical relevance for the practice of pain medicine.Relevant ...
David A. Fishbain +6 more
openalex +4 more sources