Results 281 to 290 of about 779,741 (324)

Abstract 2851: Development of an alkalizing antibody-enzyme conjugate for NSCLC treatment that is in Phase I clinical testing.

open access: closedCancer Research, 2013
Abstract Many solid human tumors generate an acidic and hypoxic microenvironment as a result of altered metabolic pathways and aberrant tumor vasculature. In certain tumors, the chronic exposure to acidic extracellular conditions has been reported to promote invasiveness and metastatic behaviour.
Baomin Tian   +4 more
openaire   +3 more sources

Helicobacter pylori stool antigen test: clinical evaluation and cost analysis of a new enzyme immunoassay. [PDF]

open access: possibleDigestive diseases and sciences, 1999
Noninvasive tests for Helicobacter pylori are increasingly used. Recently, an enzyme immunoassay for H. pylori detection in feces has been put on the market. Aim of this multicenter study was to evaluate the usefulness of this novel test as a predictor of H. pylori status in the pretreatment setting.
Trevisani, Lucio   +9 more
openaire   +2 more sources
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Is there clinical benefit to routine enzyme testing of patients on statins?

Expert Opinion on Drug Safety, 2011
Statin-treated patients undergo frequent laboratory tests. This study evaluated the clinical impact of abnormal liver or muscle enzyme results.This clinical process evaluation study took place in six primary care clinics in Israel. Four hundred and eight patients (average age 63.8 ± 10.9 years) undergoing statin treatment, with at least one enzyme ...
Shlomo Vinker   +2 more
openaire   +2 more sources

Enzyme-Linked Immunosorbent Urine Pregnancy Tests Clinical Specificity Studies

American Journal of Clinical Pathology, 1987
The performance of six recently introduced highly sensitive enzyme-linked immunosorbent (ELISA) urine pregnancy test reagent kits was evaluated for false positive results using 100 male and 100 postmenopausal female urine specimens and the findings were compared with those of a qualitative radioimmunoassay (RIA) procedure.
Mila DeLara, Z. L. Bandi, Irwin Schoen
openaire   +3 more sources

Applying and testing the conveniently optimized enzyme mismatch cleavage method to clinical DNA diagnosis

Molecular Genetics and Metabolism, 2012
Establishing a simple and effective mutation screening method is one of the most compelling problems with applying genetic diagnosis to clinical use. Because there is no reliable and inexpensive screening system, amplifying by PCR and performing direct sequencing of every coding exon is the gold standard strategy even today.
Ayano Yokoi   +4 more
openaire   +3 more sources

Validation of a strategy for HCV antibody testing with two enzyme immunoassays in a routine clinical laboratory

Journal of Clinical Virology, 2008
Centers for Disease Control (CDC) guidelines require confirmation of hepatitis C virus (HCV) screening-test-positive sera with a low signal/cut-off (S/CO) ratio by recombinant immunoblot or PCR. The UK Health Protection Agency has suggested that a second enzyme immunoassay (EIA) could be used as an alternative for confirmation in non-immunocompromised ...
Marc Van Ranst   +2 more
openaire   +3 more sources

Clinical Correlation of Toxin and Common Antigen Enzyme Immunoassay Testing in Patients With Clostridium Difficile Disease

American Journal of Gastroenterology, 2003
The aim of the present study was to assess the correlation of Triage Micro Clostridium difficile Panel and toxin B cytotoxicity assay with the clinical diagnosis of C. difficile diarrhea.The subjects evaluated were 98 patients with diarrhea for whom stool was submitted for testing for C. difficile.
Christina M. Surawicz   +4 more
openaire   +3 more sources

A Solid Phase C1q Enzyme Assay for Circulating Immune Complexes Adapted for Routine Clinical Laboratory Testing

American Journal of Clinical Pathology, 1983
An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of less than 20% in the abnormal range.
Anne L. Vahey   +3 more
openaire   +4 more sources

Enzyme Substitution in Chronic Pancreatitis: Effects on Clinical and Functional Parameters and on the Hydrogen (H2) Breath Test

Scandinavian Journal of Gastroenterology, 1986
Ten patients with chronic pancreatitis (with abdominal pain and/or diarrhoea) were treated in a double-blind multiple cross-over trial with Pankreon granules 20 g per day or placebo during three periods of one month each. Pain and bowel habits were recorded.
J Svanvik, Stockbrügger, U Armbrecht
openaire   +3 more sources

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