Results 91 to 100 of about 1,416,392 (341)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Efficacy and Safety of Intravenously Administered Tramadol in Patients with Moderate to Severe Pain Following Bunionectomy: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study

Pain and Therapy, 2020
Introduction This study is part of the registrational program for intravenously administered (IV) tramadol in the USA and compared the analgesic benefit and tolerability of two doses of IV tramadol (50 mg and 25 mg) to placebo in adult patients ...
Neil K. Singla, Richard Pollak, Ira Gottlieb, David Leiman, Harold Minkowitz, John Zimmerman, Mark Harnett, Michael Ryan, Lucy Lu, Scott Reines   +9 more
doaj   +1 more source

Antibiotic resistance evolved via inactivation of a ribosomal RNA methylating enzyme. [PDF]

, 2016
Modifications of the bacterial ribosome regulate the function of the ribosome and modulate its susceptibility to antibiotics. By modifying a highly conserved adenosine A2503 in 23S rRNA, methylating enzyme Cfr confers resistance to a range of ribosome ...
Fujimori, Danica Galonić, Noda-Garcia, Lianet, Stojković, Vanja, Tawfik, Dan S   +3 more
core  

Characterization of wild and captive baboon gut microbiota and their antibiotic resistomes [PDF]

, 2018
Antibiotic exposure results in acute and persistent shifts in the composition and function of microbial communities associated with vertebrate hosts.
Boolchandani, Manish, Chiou, Kenneth L, Dantas, Gautam, Gibson, Molly K, Jolly, Clifford J, Patel, Sanket, Pehrsson, Erica C, Phillips-Conroy, Jane E, Rogers, Jeffrey, Tsukayama, Pablo   +9 more
core   +2 more sources

Unravelling the Complexity of Colorectal Cancer: Heterogeneity, Clonal Evolution, and Clinical Implications [PDF]

, 2023
N. Saoudi Gonzalez, Francesc Salvà, Javier Ros, Iosune Baraibar, Marta Rodríguez-Castells, Ariadna García, Adriana Alcaráz, Sharela Vega, Sergio Bueno, Josep Tabernero, Élena Elez   +10 more
openalex   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

The effects of time valuation in cancer optimal therapies: a study of chronic myeloid leukemia [PDF]

, 2019
Background The mathematical design of optimal therapies to fight cancer is an important research field in today’s Biomathematics and Biomedicine given its relevance to formulate patient-specific treatments. Until now, however, cancer optimal therapies
Gutiérrez Díez, Pedro José
core   +2 more sources

Functional tricuspid regurgitation associated with left-side valvulopathy: clinical profile and long term evolution based on pulmonary pressure [PDF]

, 2023
Jairus S. Delos Reyes, P Marquez Camas, MCarmen González, D F Arroyo Monino, L Garcia Rodriguez, G Alegre Garcia, A Rodriguez Cordoba, L Palma Marti, C Pelaez Berdun, A Diaz Exposito, Nelsa González Aguado, Miguel López Tejada, Juan José Gómez‐Doblas, Manuel F. Jiménez‐Navarro, Jorge Rodríguez‐Capitán   +14 more
openalex   +1 more source

Clinical evolution of monkeypox lesions

QJM: An International Journal of Medicine, 2022
A Ordinola Navarro, C.V. Trinidad Esparza, B.A. Lopez Luis, G.M. Ruiz-Palacios   +3 more
openaire   +2 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source