Results 181 to 190 of about 9,220,792 (417)
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King+6 more
wiley +1 more source
Review: assessment of complement activation in clinical immunology laboratories: time for reappraisal? [PDF]
Mark Peakman+2 more
openalex +1 more source
Complement-mediated solubilization of immune complexes in systemic lupus erythematosus [PDF]
Thesis--University of Tsukuba, D.M.S.(B), no. 202, 1984. 5. 31Offprint. Originally published in: Clinical and experimental immunology, v. 48, pp. 37-42, 1982Joint authors: T. Fujita ...
Sakurai Tetsushi
core
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner+12 more
wiley +1 more source
Streptococcal protein SIC activates monocytes and induces inflammation
Summary: Streptococcus pyogenes is a major bacterial pathogen in the human population and isolates of the clinically important M1 serotype secrete protein Streptococcal inhibitor of complement (SIC) known to interfere with human innate immunity.
Ariane Neumann+5 more
doaj
The Allergen Immunotherapy Adverse Events Registry: Setup & methodology of a European Academy of Allergy and Clinical Immunology taskforce project. [PDF]
Asllani J+20 more
europepmc +1 more source
Objective Osteoporosis, a known complication of rheumatoid arthritis (RA), increases the risk of hip fracture, which is associated with high morbidity and mortality. Fracture risk estimates in patients with RA treated with contemporary treatment strategies are lacking.
C. Allyson Jones+5 more
wiley +1 more source
Supporting Careers of Women in Clinical Immunology: From Conceptualization to Implementation. [PDF]
Dimitriades VR+3 more
europepmc +1 more source
DEMO: Dose Exploration, Monitoring, and Optimization Using a Biological Mediator for Clinical Outcomes [PDF]
Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a truly optimal dose. because early response is not a perfect surrogate for long term therapeutic success.
arxiv