Results 181 to 190 of about 9,220,792 (417)

National Institute of Health and Care Excellence Clinical Criteria for the Diagnosis of Knee Osteoarthritis: A Prospective Diagnostic Accuracy Study in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King   +6 more
wiley   +1 more source

Complement-mediated solubilization of immune complexes in systemic lupus erythematosus [PDF]

open access: yes, 1984
Thesis--University of Tsukuba, D.M.S.(B), no. 202, 1984. 5. 31Offprint. Originally published in: Clinical and experimental immunology, v. 48, pp. 37-42, 1982Joint authors: T. Fujita ...
Sakurai Tetsushi
core  

Pharmacokinetics, Efficacy, and Safety of Upadacitinib in Pediatric Patients With Polyarticular‐Course Juvenile Idiopathic Arthritis: An Interim Analysis of an Open‐Label, Phase 1 Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner   +12 more
wiley   +1 more source

Streptococcal protein SIC activates monocytes and induces inflammation

open access: yesiScience, 2021
Summary: Streptococcus pyogenes is a major bacterial pathogen in the human population and isolates of the clinically important M1 serotype secrete protein Streptococcal inhibitor of complement (SIC) known to interfere with human innate immunity.
Ariane Neumann   +5 more
doaj  

The Allergen Immunotherapy Adverse Events Registry: Setup & methodology of a European Academy of Allergy and Clinical Immunology taskforce project. [PDF]

open access: yesClin Transl Allergy, 2023
Asllani J   +20 more
europepmc   +1 more source

Incidence of and Risk of Mortality After Hip Fractures in Rheumatoid Arthritis Relative to the General Population

open access: yesArthritis Care &Research, EarlyView.
Objective Osteoporosis, a known complication of rheumatoid arthritis (RA), increases the risk of hip fracture, which is associated with high morbidity and mortality. Fracture risk estimates in patients with RA treated with contemporary treatment strategies are lacking.
C. Allyson Jones   +5 more
wiley   +1 more source

Supporting Careers of Women in Clinical Immunology: From Conceptualization to Implementation. [PDF]

open access: yesFront Pediatr, 2022
Dimitriades VR   +3 more
europepmc   +1 more source

DEMO: Dose Exploration, Monitoring, and Optimization Using a Biological Mediator for Clinical Outcomes [PDF]

open access: yesarXiv
Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a truly optimal dose. because early response is not a perfect surrogate for long term therapeutic success.
arxiv  

Home - About - Disclaimer - Privacy