Results 71 to 80 of about 493,536 (335)

Depressed serum IgM levels in SLE are restricted to defined subgroups [PDF]

open access: yes, 2017
Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE) patients, divided into subgroups based on distinct autoantibody profiles. Depressed IgM levels were more common in SLE than in matched population controls.
arxiv   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

"THE TEACHER! BEFORE YOUR NAME..." (to the 120 th anniversary of Vladimir Ilyich Ioffe)

open access: yesИнфекция и иммунитет, 2018
February 14th 2018 —  anniversary of the famous scientist, academician of the USSR Academy of Medical Sciences, great immunologist and microbiologist Vladimir Ilyich Ioffe the founder of the Russian school of clinical and epidemiological immunology.
Artem A. Totolian
doaj   +1 more source

Mondrian Processes for Flow Cytometry Analysis [PDF]

open access: yesarXiv, 2017
Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This dependence on human annotation limits the rate, reproducibility, and complexity of flow cytometry analysis.
arxiv  

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

open access: yesAging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Protocol for oral transplantation of maternal fecal microbiota to newborn infants born by cesarean section

open access: yesSTAR Protocols, 2021
Summary: Infants born by cesarean section have an intestinal microbiota that differs from that of infants delivered vaginally. Here, we report a protocol for performing oral transplantation of maternal fecal microbiota to newborn infants born by elective
Otto Helve   +6 more
doaj  

Important questions in drug allergy and hypersensitivity: consensus papers from the 2018 AAAAI/WAO international drug allergy symposium

open access: yesWorld Allergy Organization Journal, 2018
This article is one of a series of international consensus documents developed from the International Drug Allergy Symposium held at the Joint Congress of the American Academy of Allergy, Asthma & Immunology/World Allergy Organization on March 1, 2018 ...
Pascal Demoly, Mariana Castells
doaj   +1 more source

Immune-Mediated Anemias: Clinical Immunology Learning Module

open access: yesMedEdPORTAL, 2015
Introduction Cognitive studies have demonstrated that learning the cause-and-effect relationship between basic sciences and clinical features improves the learner's diagnostic ability.
Dolgor Baatar, Cynthia Perry
doaj   +1 more source

Utilization of high-fidelity simulation to address challenges with the basic science immunology education of preclinical medical students

open access: yesBMC Medical Education, 2019
Background Immune function and dysfunction are highly complex basic science concepts introduced in the preclinical medical school curriculum. A challenge for early learners is connecting the intricate details and concepts in immunology with clinical ...
Marie Cavuoto Petrizzo   +6 more
doaj   +1 more source

Maximum Matchings in Graphs for Allocating Kidney Paired Donation [PDF]

open access: yesarXiv, 2017
Relatives and friends of an end-stage renal disease patient who offer to donate a kidney are often found to be incompatible with their intended recipients. Kidney paired donation matches one patient and his incompatible donor with another patient and donor in the same situation for an organ exchange.
arxiv  

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