Results 71 to 80 of about 5,291,655 (156)

Epileptic–Dyskinetic Encephalopathy Associated with a PPP3CA Variant: Expansion of the Phenotypic Spectrum

Movement Disorders Clinical Practice, EarlyView.
Bruno Antunes Contrucci, Ursula Thomé, Larissa Aparecida Batista, Ana Laura Volpi Martins Lorenzoni, Carla Andrea Cardoso Tanuri Caldas, Americo Ceiki Sakamoto, Israel Gomy, Lisandra Mesquita Batista, Marcela Lopes de Almeida, Ana Paula Andrade Hamad, Guillermo Andrey Ariza Traslaviña   +10 more
wiley   +1 more source

Serum‐derived microribonucleic acids as potential novel biomarkers for slowly progressive type 1 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
This study evaluated serum miRNAs as biomarkers in adult patients with SPIDDM. Serum miRNAs were measured at the time of SPIDDM (probable) diagnosis, and miR‐150‐5p was inversely associated with CPI at the last outpatient visit, suggesting its potential utility for predicting subsequent insulin secretory decline.
Hideyuki Okuma, Takahiro Tsutsumi, Masashi Ichijo, Tetsuro Kobayashi, Kyoichiro Tsuchiya   +4 more
wiley   +1 more source

Clinical, biochemical and histological changes during developement of pregnancy ketosis in goats [PDF]

, 2016
Thin does or very over-conditioned does and does carrying with multiple pregnancies are more likely to develop pregnancy ketosis (pregnancy toxaemia). Pregnancy ketosis is one of the metabolic disorders in ruminant animal such as does and ewes during the
Md. Ajat, Mohd Mokrish, Abu Bakar @ Zakaria, Md Zuki, Amirul, F. M. A., Lai, Kok Song, Abu Hassim, Hasliza, Saad, Mohd Zamri   +5 more
core   +2 more sources

Type 1 diabetes in the era of obesity: Pathophysiology and therapeutic implications

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Type 1 diabetes is defined by immune‐mediated beta‐cell failure and dependence on exogenous insulin. That definition is correct, but it may not fully describe many people seen in current clinical practice. Overweight and obesity are now common in type 1 diabetes, leading to variable combinations of high insulin requirement, hypertension ...
Zachary Bloomgarden
wiley   +1 more source

Cullin 3 mitigates nonesterified fatty acid–induced oxidative stress in mammary epithelial cells: Involvement of BCL2/BECN1 and autophagy

Journal of Dairy Science
: High nonesterified fatty acid (NEFA) concentrations in cows with clinical ketosis lead to metabolic dysfunction in mammary cells, resulting in oxidative stress.
Yifei Dong, Wenwen Gao, Kai Liu, Cai Lin, Muhammad Usman, Juan J. Loor, Guojin Li, Liguang Cao, Zifeng Yang, Jianchun Luo, Depeng Li, Qianwen Sun, Lin Lei, Xiliang Du, Yuxiang Song, Guowen Liu, Xinwei Li   +16 more
doaj   +1 more source

PHB2-mediated inhibition of OPA1 cleavage alleviates nonesterified fatty acid–induced apoptosis in bovine mammary epithelial cells

Journal of Dairy Science
: Excessive nonesterified fatty acids (NEFA) during the transition period impose metabolic stress on the bovine mammary gland. High NEFA levels induce oxidative stress and trigger apoptosis in bovine mammary epithelial cells.
Guojin Li, Qi Shao, Qingyan Yin, Kai Liu, Liguang Cao, Jianchun Luo, Depeng Li, Qianwen Sun, Lin Lei, Yuxiang Song, Xiliang Du, Xinwei Li, Guowen Liu, Wenwen Gao   +13 more
doaj   +1 more source

Clinical characteristics and disease progression of typical adult‐onset type 1 diabetes and insulin‐dependent latent autoimmune diabetes in adults

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims We investigated the characteristics of typical adult‐onset type 1 diabetes (T1D) and insulin‐dependent latent autoimmune diabetes in adults (LADA) in Thailand. Methods This retrospective chart review enrolled typical T1D and insulin‐dependent LADA patients diagnosed at age ≥30 years, and who were followed up at Siriraj Hospital, Thailand,
Chanoknan Luksameejaroenchai, Thanida Tangjarusritaratorn, Lukana Preechasuk   +2 more
wiley   +1 more source

Evaluation of renal and hepatic functions in cattle with subclinical and clinical ketosis

, 2016
The purpose of this study was to research the changes in renal and hepatic functions of high productive dairy cows diagnosed with subclinical and clinical ketosis. The material of the study consisted of 30 dairy cows of high milk production. Diagnosis of
Mustafa İssi, Yusuf Gül, Onur Başbuğ
core   +1 more source

Open versus minimally invasive surgical techniques for displaced abomasum in dairy cattle: A systematic review and meta‐analysis

Veterinary Surgery, EarlyView.
Abstract Objectives To compare open and minimally invasive surgical approaches for the treatment of abomasal displacement (AD) in dairy cows regarding effectiveness (mortality, recurrence, milk yield, and complications) and efficiency (operative time).
Uygur Canatan, Vildan Aslan Canatan
wiley   +1 more source

Identification of key factors causing ketosis in dairy cows with low feed intake

Animal Biotechnology
Ketosis is a common metabolic disease in high-yield dairy cows. Key genes affecting ketosis need to be further explored by new methods. The gene expression profiling and clinical data of GSE92398, GSE104079, and GSE4304 were obtained from the gene ...
Xue Feng, Qi Feng, Sayed Haidar Abbas Raza, Fen Li, Yun Ma   +4 more
doaj   +1 more source