Results 51 to 60 of about 1,313,556 (294)

Early and efficient detection of Mycobacterium tuberculosis in sputum by microscopic observation of broth cultures. [PDF]

, 2013
Early, efficient and inexpensive methods for the detection of pulmonary tuberculosis are urgently needed for effective patient management as well as to interrupt transmission. These methods to detect M. tuberculosis in a timely and affordable way are not
A Cattamanchi, AD Harries, Benson R. Kidenya, CC Boehme, DA Moore, DA Moore, Daniel W. Fitzgerald, EF Lyamuya, F Ardito, G Shiferaw, GS Ejigu, GV Mukamolova, HP Chien, J Minion, JL Davis, JS Michael, JW Pape, L Caviedes, Lauren E. Webster, Madhukar Pai, N Kiraz, NM Buderer, PD Davies, PE Farmer, PW Ndung’u, Robert N. Peck, Rodrick Kabangila, RP Lazarus, S Keshavjee, Serena P. Koenig, Stephen E. Mshana, W Zhu, Warren D. Johnson, WG Park   +33 more
core   +8 more sources

Intestinal Parasitic Infections in Patients Attending Gastrointestinal Clinics

Journal of Mazandaran University of Medical Sciences, 2017
Background and purpose: Accurate information on clinical and laboratory findings of parasitic diseases in medical centers could be effective in evaluating various aspects of their disease. Therefore, the aim of this study was to evaluate the clinical and
Niloofar Amin, Hafez Tirger Fakhri, Vahid Hossini, Hajare Ziaei, Azadeh Dadashi, Bahman Rahimi, Shirzad Gholami   +6 more
doaj  

TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models

Journal of Innate Immunity
Introduction: Escherichia coli (E. coli) is a significant commensal gram-negative bacterium that can give rise to various diseases. The roles of Toll-like receptor 2 (TLR2) and the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome ...
Zhiguo Gong, Wei Mao, Jiamin Zhao, Peipei Ren, Zhuoya Yu, Yunjie Bai, Chao Wang, Yuze Liu, Shuang Feng, Surong Hasi   +9 more
doaj   +1 more source

Why Test study protocol: a UK-wide audit using the Primary Care Academic CollaboraTive (PACT) to explore the reasons for primary care testing

BJGP Open, 2022
Background: The number of blood tests done in primary care has been increasing over the past 20 years. Some estimates suggest that up to one-quarter of these tests may not have been needed.
Alexander Burrell, Polly Duncan, Ian Bennett-Britton, Sam Hodgson, Samuel WD Merriel, Salman Waqar, Penny Whiting, Jessica Watson, on behalf of the Primary Care Academic Collaborative (PACT)   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An underlying mechanism of bovine mastitis: PGE2 regulates Staphylococcus aureus-induced inflammatory response through TLR2, TLR4, and NLRP3 in macrophages

Veterinary Quarterly
Staphylococcus aureus (S. aureus) evades host immunity by modulating macrophage functions, including immune regulation and phagocytosis, ultimately contributing to bovine mastitis. This study aimed to elucidate the molecular mechanisms of S.
Zhiguo Gong, Zhuoya Yu, Peipei Ren, Shuangyi Zhang, Ruifeng Gao, Jiamin Zhao, Yixin Wang, Shaojie Qin, Wenhui Bao, Shuang Feng   +9 more
doaj   +1 more source

Prevalence and genetic diversity of human diarrheagenic Escherichia coli isolates by multilocus sequence typing

International Journal of Infectious Diseases, 2018
Background: The population structure of human diarrheagenic Escherichia coli (DEC) isolates derived from worldwide collections remains undefined. Methods: A total of 1196 clinical isolates were obtained from a multilocus sequence typing (MLST) database ...
Fei Yu, Xiao Chen, Shufa Zheng, Dongsheng Han, Yiyin Wang, Ruonan Wang, Baohong Wang, Yu Chen   +7 more
doaj   +1 more source

COVID-19: laboratory diagnosis for clinicians. An updating article

São Paulo Medical Journal, 2020
COVID-19 (coronavirus disease 2019) is an infectious disease caused by the new coronavirus associated with severe acute respiratory syndrome 2 (SARS-CoV-2).
Luisane Maria Falci Vieira, Eduardo Emery, Adagmar Andriolo   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Clinical risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in Mali

International Journal of Infectious Diseases, 2019
Background: MDR-TB is a major threat to global TB control. In 2015, 580,000 were treated for MDR-TB worldwide. The worldwide roll-out of GeneXpert MTB/RIF® has improved diagnosis of MDR-TB; however, in many countries laboratories are unable to assess ...
Bocar Baya, Chad J. Achenbach, Bourahima Kone, Yacouba Toloba, Djeneba K. Dabitao, Bassirou Diarra, Drissa Goita, Seydou Diabaté, Mamoudou Maiga, Dianguina Soumare, Khadidia Ouattara, Tenin Kanoute, Gaoussou Berthe, Youssouf M. Kamia, Yeya dit Sadio Sarro, Moumine Sanogo, Antieme C.G. Togo, Bindongo P.P. Dembele, Nadie Coulibaly, Amadou Kone, Maxwell Akanbi, Michael Belson, Sounkalo Dao, Susan Orsega, Sophia Siddiqui, Seydou Doumbia, Robert L. Murphy, Souleymane Diallo   +27 more
doaj   +1 more source