Results 71 to 80 of about 734,729 (308)

PCR-Based Techniques for Leprosy Diagnosis: From the Laboratory to the Clinic

PLoS Neglected Tropical Diseases, 2014
In leprosy, classic diagnostic tools based on bacillary counts and histopathology have been facing hurdles, especially in distinguishing latent infection from active disease and diagnosing paucibacillary clinical forms. Serological tests and IFN-gamma releasing assays (IGRA) that employ humoral and cellular immune parameters, respectively, are also ...
Alejandra Nóbrega Martinez, Carolina Talhari, Milton Ozório Moraes, Sinésio Talhari   +3 more
openaire   +4 more sources

Laboratory medicine best practices : developing an evidence- based review and evaluation process. Final technical report 2007: Phase I. [PDF]

Clinical laboratory services play a vital role in the delivery of individual health care and public health in the United States. The U.S. Department of Health and Human Services\ue2\u20ac\u2122 (HHS) Centers for Medicare & Medicaid Services (CMS ...

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Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Extensively drug resistant tuberculosis in Mali: a case report

BMC Research Notes, 2017
Background Drug resistant tuberculosis presents a major public health challenge. Case presentation We present here the first two patients diagnosed with extensively drug resistant tuberculosis in Bamako, Mali.
Bassirou Diarra, Yacouba Toloba, Bakary Konate, Moumine Sanogo, Antieme Combo Georges Togo, Fatimata Camara, Gaoussou Berthe, Dianguina Soumaré, Bocar Baya, Drissa Goita, Yeya dit Sadio Sarro, Mamoudou Maiga, Michael Belson, Susan Orsega, Sounkalo Dao, Robert L. Murphy, Sophia Siddiqui, Bouke C. de Jong, Seydou Doumbia, Souleymane Diallo   +19 more
doaj   +1 more source

Center for Surveillance, Epidemiology, and Laboratory Services : our services. our work. our impact [PDF]

CSELS was established at the Centers for Disease Control and Prevention (CDC) in October 2013, although the roots of our center are as old as CDC itself. CSELS tracks America\ue2\u20ac\u2122s health, strengthens laboratory networks, and helps to identify

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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

SPARK EROSION IMPLANT-SUPPORTED OVERDENTURES: CLINICAL AND LABORATORY TECHNIQUES

Implant Dentistry, 1992
Overdentures can be utilized effectively in treatment plans involving implants. Usually soft tissue support is necessary, which requires a conventional denture base. Implant-supported overdentures do not require conventional denture base extension unless necessitated by functional or esthetic considerations.
T J, Salinas, I M, Finger, J J, Thaler, R S, Clark   +3 more
openaire   +3 more sources

Laboratory medicine : a national status report [PDF]

Although the U.S. ranks highest in per capita health care spending, there is overwhelming evidence of gaps between well-founded standards of care and health care practice. The Institute of Medicine reports, To Err is Human: Building a Safer Health System

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Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Transcriptome Approach Evaluating the Effects of Atractylenolide I on the Secretion of Estradiol and Progesterone in Feline Ovarian Granulosa Cells

Veterinary Sciences
Atractylodes macrocephala Koidz (AMK) as an oriental medicine has been used in the treatment of threatened abortion. Atractylenolide I (AT-I) is one of the major bioactive components of AMK.
Yuli Guo, Junping Liu, Shuangyi Zhang, Di Sun, Zhiying Dong, Jinshan Cao   +5 more
doaj   +1 more source