Results 61 to 70 of about 1,313,556 (294)
Gut Pathogens, 2020 Background Helicobacter pylori bacterium is a major cause of gastritis. With increasing use of antibiotics to treat infections, mutation resistant strains have emerged in most human populations.
Yangxia Li +7 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Portal vein hypoplasia in dogs [PDF]
, 2014 Portal vein hypoplasia (PVH) is a congenital disorder, in which microscopic intrahepatic shunts are present, causing blood to bypass the liver sinusoids.
De Cock, HEV +6 more
core
The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea [PDF]
, 2011 Purpose: A high prevalence of depressive symptomatology has been reported amongst sufferers of obstructive sleep apnea (OSA), but it remains unclear as to whether this is due to their OSA or other factors associated with the disorder.
Downey, Luke +5 more
core +1 more source
Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants
Research and Practice in Thrombosis and Haemostasis, 2022 Background Lupus anticoagulants (LA) are one laboratory criterion for classification of antiphospholipid syndrome, with presence of vascular thrombosis and/or pregnancy/fetal morbidity being clinical criteria. The presence of LA is detected (or excluded)
Emmanuel J. Favaloro, Leonardo Pasalic
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]
, 2009 The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core +1 more source
rds: mucopolysaccharidoses; glycosaminoglycans; clinical laboratory techniques; biological markers
Paediatria Croatica, 2013 U rastućem broju nasljednih metaboličkih bolesti lizosomske bolesti nakupljanja čine relativno malu skupinu od 60-tak bolesti. Njihova podskupina, mukopolisaharidoze (MPS), obuhvaća samo sedam tipova bolesti (uz podtipove), koje su zbog patofi ziološkekompleksnosti, progresivnog tijeka, multiorganske zahvaćenosti te izrazite kliničke heterogenosti i ...
Ksenija Fumić +4 more
openaire +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Use and positivity of laboratory tests at Las Tunas provincial hospital
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017 Background: the laboratories must offer the tests to aid doctors in their clinical practice, providing them with the information for the diagnosis, prevention or treatment of diseases.Objective: to describe the use of tests which have been at the doctors’
Jenny de la Caridad Hernández Betancourt +4 more
doaj