Results 61 to 70 of about 878,073 (326)

Efficiency over thoroughness in laboratory testing decision making in primary care: findings from a realist review

open access: yesBJGP Open, 2021
Background: Existing research demonstrates significant variation in test-ordering practice, and growth in the use of laboratory tests in primary care. Reviews of interventions designed to change test-ordering practice report heterogeneity in design and ...
Claire Duddy, Geoff Wong
doaj   +1 more source

Demand Forecasting for Platelet Usage: from Univariate Time Series to Multivariate Models [PDF]

open access: yesarXiv, 2021
Platelet products are both expensive and have very short shelf lives. As usage rates for platelets are highly variable, the effective management of platelet demand and supply is very important yet challenging. The primary goal of this paper is to present an efficient forecasting model for platelet demand at Canadian Blood Services (CBS).
arxiv  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

open access: yesMolecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina   +17 more
wiley   +1 more source

Use and positivity of laboratory tests at Las Tunas provincial hospital

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2017
Background: the laboratories must offer the tests to aid doctors in their clinical practice, providing them with the information for the diagnosis, prevention or treatment of diseases.Objective: to describe the use of tests which have been at the doctors’
Jenny de la Caridad Hernández Betancourt   +4 more
doaj  

Comparative Evaluation of Three Preprocessing Methods for Extraction and Detection of Influenza A Virus Nucleic Acids from Sputum

open access: yesFrontiers in Medicine, 2018
Viscous sputum specimens usually cannot undergo automated extraction, and thus, a pre-homogenization process is desirable before isolating nucleic acids for real-time reverse transcription PCR.
Fei Yu   +6 more
doaj   +1 more source

An illustrated review of bleeding assessment tools and common coagulation tests

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Recognizing the complexity of coagulation tests and currently used anticoagulants, we developed this illustrated review on bleeding assessment tools and common coagulation screening tests.
Carolyne Elbaz, Michelle Sholzberg
doaj   +1 more source

Evaluation of Galaxy as a User-friendly Bioinformatics Tool for Enhancing Clinical Diagnostics in Genetics Laboratories [PDF]

open access: yesInternational Journal on Bioinformatics & Biosciences (IJBB), 4(3), 19-40 (2024)
Bioinformatics platforms have significantly changed clinical diagnostics by facilitating the analysis of genomic data, thereby advancing personalized medicine and improving patient care. This study examines the integration, usage patterns, challenges, and impact of the Galaxy platform within clinical diagnostics laboratories.
arxiv   +1 more source

Vehicle Noise: Comparison of Loudness Ratings in the Field and the Laboratory [PDF]

open access: yesarXiv, 2022
Objective: Distorted loudness perception is one of the main complaints of hearing aid users. Being able to measure loudness perception correctly in the clinic is essential for fitting hearing aids. For this, experiments in the clinic should be able to reflect and capture loudness perception as in everyday-life situations.
arxiv  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Extensively drug resistant tuberculosis in Mali: a case report

open access: yesBMC Research Notes, 2017
Background Drug resistant tuberculosis presents a major public health challenge. Case presentation We present here the first two patients diagnosed with extensively drug resistant tuberculosis in Bamako, Mali.
Bassirou Diarra   +19 more
doaj   +1 more source

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