Results 51 to 60 of about 927,791 (328)

Using alternative teaching and learning approaches to deliver clinical microbiology during the COVID-19 pandemic [PDF]

, 2021
Lovleen Tina Joshi
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Clinical microbiology: Should microbiology be a clinical or a laboratory speciality?

Indian Journal of Pathology and Microbiology, 2010
Clinical microbiology is a specific combination of knowledge, attitude and practice aimed at direct clinical involvement in infectious disease management using the core principles of medical microbiology and clinical medicine.
Bhattacharya Sanjay
doaj  

Culture of Clinical Specimens Reveals Extensive Diversity of Legionella pneumophila Strains in Arizona

mSphere, 2019
Between 2000 and 2017, a total of 236 Legionella species isolates from Arizona were submitted to the CDC for reference testing. Most of these isolates were recovered from bronchoalveolar lavage specimens.
Brian H. Raphael, Trung Huynh, Ellen Brown, Jessica C. Smith, Irene Ruberto, Linda Getsinger, Stacy White, Jonas M. Winchell   +7 more
doaj   +1 more source

Evidence-Based Clinical Microbiology [PDF]

Journal of Clinical Microbiology, 2000
Since 1994, the JAMA Guides have been advising clinicians how to use articles about diagnostic tests ([5][1], [6][2], [16][3]). Consistent with the principles of evidence-based medicine (EBM), clinicians are first expected to assess the validity of a test and then to decide whether it is ...
openaire   +2 more sources

Friend and foe: factors influencing the movement of the bacterium Helicobacter pylori along the parasitism-mutualism continuum. [PDF]

, 2014
Understanding the transition of bacterial species from commensal to pathogen, or vice versa, is a key application of evolutionary theory to preventative medicine.
Koskella, Britt, Lin, Derek
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Glymphatic system dysfunction in recovered patients with mild COVID-19: A DTI-ALPS study

iScience
Summary: Central nervous sequelae are often reported in recovered patients with COVID-19. It is not clear whether recovered COVID-19 patients have glymphatic impairment and clinical correlation.
Lin Wu, Zhi Zhang, Xiao Liang, Yao Wang, Yuan Cao, Meng Li, Fuqing Zhou   +6 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

TRIF-IFN-I pathway in Helicobacter-induced gastric cancer in an accelerated murine disease model and patient biopsies

iScience
Summary: Helicobacter pylori (H. pylori) infection is a known cause of many digestive diseases, including gastritis, peptic ulcers, and gastric cancer. However, the underlying mechanisms by which H. pylori infection triggers these disorders are still not
Prerna Bali, Ivonne Lozano-Pope, Jonathan Hernandez, Monica V. Estrada, Maripat Corr, Michael A. Turner, Michael Bouvet, Christopher Benner, Marygorret Obonyo   +8 more
doaj   +1 more source